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CD25/IL-2R alpha Antibody (Hu107) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
Hu107
Clonality
Monoclonal
Host
Human
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB9926U-100UG
Alexa Fluor 405
FAB9926V-100UG
Alexa Fluor 488
FAB9926G-100UG
Alexa Fluor 532
FAB9926X
Alexa Fluor 594
FAB9926T-100UG
Alexa Fluor 647
FAB9926R-100UG
Alexa Fluor 700
FAB9926N-100UG
Alexa Fluor 750
FAB9926S-100UG
Allophycocyanin
FAB9926A
Allophycocyanin/Cy7
FAB9926APCCY7
Biotin
FAB9926B
DyLight 350
FAB9926D
DyLight 405
FAB9926E
DyLight 488
FAB9926K
DyLight 550
FAB9926L
DyLight 594
FAB9926M
DyLight 650
FAB9926W
DyLight 680
FAB9926Y
DyLight 755
FAB9926Z
FITC
FAB9926F
HRP
FAB9926H
Janelia Fluor 525
FAB9926JF525
Janelia Fluor 549
FAB9926I
Janelia Fluor 585
FAB9926JF585
Janelia Fluor 635
FAB9926JF635
Janelia Fluor 646
FAB9926J
Janelia Fluor 669
FAB9926JF669
PE
FAB9926P
PE/Atto594
FAB9926PEATT594
PE/Cy5.5
FAB9926PECY55
PE/Cy7
FAB9926PECY7
PerCP
FAB9926C
Unconjugated
MAB9926-100
mFluor Violet 450 SE
FAB9926MFV450
mFluor Violet 500 SE
FAB9926MFV500
mFluor Violet 610 SE
FAB9926MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB9926-100
Carrier Free
MAB9926-100
Carrier Free
MAB9926-SP
Carrier Free
FAB9926V-100UG
Carrier Free
FAB9926U-100UG
Carrier Free
FAB9926T-100UG
Carrier Free
FAB9926S-100UG
Carrier Free
FAB9926R-100UG
Carrier Free
FAB9926N-100UG
Carrier Free
FAB9926G-100UG
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CD25/IL-2R alpha Antibody (Hu107) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Additional Information
Recombinant Monoclonal Antibody For Research Use Only
Immunogen
Human CD25/IL-2 R alpha
Specificity
Detects Human CD25/IL-2 R alpha based on Basiliximab therapeutic antibody. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Basiliximab. This product is for research use only.
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for CD25/IL-2R alpha Antibody (Hu107) [CoraFluor™ 1]

  • CD25 antigen
  • CD25
  • IDDM10
  • IL-2 R alpha
  • IL-2 receptor subunit alpha
  • IL2R alpha
  • IL-2R subunit alpha
  • IL2R
  • IL2RA
  • IL-2Ra
  • IL-2-RA
  • IL2-RA
  • interleukin 2 receptor, alpha
  • interleukin-2 receptor subunit alpha
  • p55
  • TAC antigen
  • TCGFR

Background

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.(provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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