CD25/IL-2R alpha Products

Description

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.(provided by RefSeq)

Bioinformatics

Entrez	16184 Mouse 25704 Rat 3559 Human
Uniprot	AAI56628.1 Human NP_000408 Human NP_000408.1 Human NP_000869 Human P01589 Human P01590 Mouse
Product By Gene ID	3559
Alternate Names	CD25 antigen CD25 IDDM10 IL-2 receptor subunit alpha IL-2R subunit alpha IL2R IL-2-RA IL2-RA interleukin 2 receptor, alpha interleukin-2 receptor subunit alpha p55 TAC antigen TCGFR

Research Areas for CD25/IL-2R alpha

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Apoptosis
Biologically Active Proteins
CD Markers
Cytokine Research
Diabetes Research
Immunology
Innate Immunity
Mast Cell Markers
Signal Transduction