Home » CD25/IL-2R alpha » CD25/IL-2R alpha Antibodies » CD25/IL-2R alpha Antibody (Basiliximab) [PE/Atto594] - Chimeric
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CD25/IL-2R alpha Antibody (Basiliximab) [PE/Atto594] - Chimeric

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Product Details

Summary
Reactivity Hu, Pm-Cm, RMSpecies Glossary
Applications Flow
Clone
Basiliximab
Clonality
Monoclonal
Host
Rabbit
Conjugate
PE/Atto594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-52661AF350
Alexa Fluor 405
NBP2-52661AF405
Alexa Fluor 488
NBP2-52661AF488
Alexa Fluor 532
NBP2-52661AF532
Alexa Fluor 594
NBP2-52661AF594
Alexa Fluor 647
NBP2-52661AF647
Alexa Fluor 700
NBP2-52661AF700
Alexa Fluor 750
NBP2-52661AF750
Allophycocyanin
NBP2-52661APC
Biotin
NBP2-52661B
DyLight 350
NBP2-52661UV
DyLight 405
NBP2-52661V
DyLight 488
NBP2-52661G
DyLight 550
NBP2-52661R
DyLight 594
NBP2-52661DL594
DyLight 650
NBP2-52661C
DyLight 680
NBP2-52661FR
DyLight 755
NBP2-52661IR
FITC
NBP2-52661F
HRP
NBP2-52661H
Janelia Fluor 549
NBP2-52661JF549
Janelia Fluor 646
NBP2-52661JF646
PE
NBP2-52661PE
PE/Cy5.5
NBP2-52661PECY55
PE/Cy7
NBP2-52661PECY7
PerCP
NBP2-52661PCP
Unconjugated
NBP2-52661-0.2mg
mFluor Violet 450 SE
NBP2-52661MFV450
mFluor Violet 500 SE
NBP2-52661MFV500
mFluor Violet 610 SE
NBP2-52661MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-52661-0.2mg
Azide and BSA Free
NBP2-52661-0.2mg
Azide and BSA Free
NBP2-52661-0.025mg
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CD25/IL-2R alpha Antibody (Basiliximab) [PE/Atto594] - Chimeric Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Specificity
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
IL2RA
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for CD25/IL-2R alpha Antibody (Basiliximab) [PE/Atto594] - Chimeric

  • CD25 antigen
  • CD25
  • IDDM10
  • IL-2 R alpha
  • IL-2 receptor subunit alpha
  • IL2R alpha
  • IL-2R subunit alpha
  • IL2R
  • IL2RA
  • IL-2Ra
  • IL-2-RA
  • IL2-RA
  • interleukin 2 receptor, alpha
  • interleukin-2 receptor subunit alpha
  • p55
  • TAC antigen
  • TCGFR

Background

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.(provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IL2RA