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CD1b Antibody (737249) [Unconjugated]

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MOLT‑4 human acute lymphoblastic leukemia cell line was stained with Mouse Anti-Human CD1b Monoclonal Antibody (Catalog # MAB7446, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B).
MOLT‑4 human acute lymphoblastic leukemia cell line was stained with Mouse Anti-Human CD1b Monoclonal Antibody (Catalog # MAB7446, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
737249
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7446U-100UG
Alexa Fluor 405
FAB7446V-100UG
Alexa Fluor 488
FAB7446G-100UG
Alexa Fluor 532
FAB7446X
Alexa Fluor 594
FAB7446T-100UG
Alexa Fluor 647
FAB7446R-100UG
Alexa Fluor 700
FAB7446N-100UG
Alexa Fluor 750
FAB7446S-100UG
Allophycocyanin/Cy7
FAB7446APCCY7
Biotin
FAB7446B
DyLight 350
FAB7446D
DyLight 405
FAB7446E
DyLight 488
FAB7446K
DyLight 550
FAB7446L
DyLight 594
FAB7446M
DyLight 650
FAB7446W
DyLight 680
FAB7446Y
DyLight 755
FAB7446Z
FITC
FAB7446F
HRP
FAB7446H
Janelia Fluor 549
FAB7446I
Janelia Fluor 646
FAB7446J
PE/Atto594
FAB7446PEATT594
PE/Cy5.5
FAB7446PECY55
PE/Cy7
FAB7446PECY7
PerCP
FAB7446C
mFluor Violet 450 SE
FAB7446MFV450
mFluor Violet 500 SE
FAB7446MFV500
mFluor Violet 610 SE
FAB7446MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB7446-SP
Carrier Free
FAB7446V-100UG
Carrier Free
FAB7446U-100UG
Carrier Free
FAB7446T-100UG
Carrier Free
FAB7446S-100UG
Carrier Free
FAB7446R-100UG
Carrier Free
FAB7446N-100UG
Carrier Free
FAB7446G-100UG
100% Guarantee on every product

CD1b Antibody (737249) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human CD1b
Ser18-Ser303
Accession # P29016
Specificity
Detects human CD1b in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) CD1a, rhCD1c, rhCD1d, rhCD1e, recombinant mouse (rm) CD1d1, or rmCD1d2 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CD1B
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
Publications
Read Publication using
MAB7446 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD1b Antibody (737249) [Unconjugated]

  • CD1
  • CD1A
  • CD1b antigen
  • CD1B antigen, b polypeptide
  • CD1b molecule
  • CD1b
  • cortical thymocyte antigen CD1B
  • differentiation antigen CD1-alpha-3
  • MGC125990
  • MGC125991
  • R1
  • T-cell surface glycoprotein CD1b

Background

CD1b is an approximately 40-50 kDa transmembrane glycoprotein in the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1b associates with beta 2-microglobulin in endosomes and the Golgi where it facilitates the processing of glycolipids for their presentation by other CD1 family proteins. CD1b is expressed by most nonhuman mammals but not by mice or rats. It contains one Ig-like domain in its extracellular region. Alternate splicing of human CD1b generates an additional isoform that lacks 55 amino acids of the Ig-like domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD1b Antibody (MAB7446)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


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Bioinformatics

Gene Symbol CD1B
Uniprot