MOLT‑4 human acute lymphoblastic leukemia cell line was stained with Mouse Anti-Human CD1b Monoclonal Antibody (Catalog # MAB7446, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), ...read more
Mouse myeloma cell line NS0-derived recombinant human CD1b Ser18-Ser303 Accession # P29016
Specificity
Detects human CD1b in direct ELISAs.
In direct ELISAs, no cross-reactivity
with recombinant human (rh) CD1a, rhCD1c, rhCD1d, rhCD1e, recombinant mouse (rm)
CD1d1, or rmCD1d2 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CD1B
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CD1b Antibody (737249) [Unconjugated]
CD1
CD1A
CD1b antigen
CD1B antigen, b polypeptide
CD1b molecule
CD1b
cortical thymocyte antigen CD1B
differentiation antigen CD1-alpha-3
MGC125990
MGC125991
R1
T-cell surface glycoprotein CD1b
Background
CD1b is an approximately 40-50 kDa transmembrane glycoprotein in the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1b associates with beta 2-microglobulin in endosomes and the Golgi where it facilitates the processing of glycolipids for their presentation by other CD1 family proteins. CD1b is expressed by most nonhuman mammals but not by mice or rats. It contains one Ig-like domain in its extracellular region. Alternate splicing of human CD1b generates an additional isoform that lacks 55 amino acids of the Ig-like domain.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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