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CD11c Antibody (SI19-06)

Images

 
Immunohistochemistry-Paraffin: CD11c Antibody (SI19-06) [NBP2-67402] - Analysis of paraffin-embedded human tonsil tissue using anti-CD11c antibody. Counter stained with hematoxylin.
Immunohistochemistry-Paraffin: CD11c Antibody (SI19-06) [NBP2-67402] - Analysis of paraffin-embedded human spleen tissue using anti-CD11c antibody. Counter stained with hematoxylin.
Immunohistochemistry-Paraffin: CD11c Antibody (SI19-06) [NBP2-67402] - Human lymph node. CD11c antibody at 1:200, RT for 30 minutes. IHC-P image submitted by a verified customer review.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP, Func
Clone
SI19-06
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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CD11c Antibody (SI19-06) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Synthetic peptide within Human CD11c aa 1,114-1,163 / 1,163 (Cytoplasmic). (SwissProt: P20702 Human)
Localization
Membrane.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
ITGAX
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:500
  • Immunoprecipitation
  • Multiplex Immunoassay Multiplex IHC: 1:1000
  • Western Blot 1:500
Application Notes
IP-Use at an assay dependent concentration.
Reviewed Applications
Read 1 Review rated 4
using
NBP2-67402 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
TBS (pH7.4), 0.05% BSA, 40% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for CD11c Antibody (SI19-06)

  • 95 alpha chain
  • 95
  • 95, alpha subunit
  • CD11 antigen-like family member C
  • CD11c antigen
  • CD11c
  • CD11Cleu M5, alpha subunit
  • Integrin alpha X
  • integrin alpha-X
  • integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
  • integrin, alpha X (complement component 3 receptor 4 subunit)
  • ITGAX
  • Leu M5
  • Leukocyte adhesion glycoprotein p150
  • Leukocyte adhesion receptor p150
  • leukocyte surface antigen p150
  • myeloid membrane antigen, alpha subunit
  • p150 95 integrin alpha chain
  • p150,95 alpha
  • SLEB6

Background

CD11c encodes the integrin alpha X chain protein. CD11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD11c Antibody (NBP2-67402) (0)

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Review for CD11c Antibody (NBP2-67402) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NBP2-67402:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin CD11c NBP2-67402
Enlarge
4
reviewed by:
Verified Customer
IHC-P Human 09/17/2019
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedLymph node
SpeciesHuman
LotHM0325

Comments

Comments1:200 @ room temperature for 30 minutes

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for CD11c Antibody (NBP2-67402) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

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Array NBP2-67402

Research Areas for CD11c Antibody (NBP2-67402)

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Blogs on CD11c.


  Read full blog post.

CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity
Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a...  Read full blog post.

Adhesion Receptor Molecule CD11b/c is the Point of Entry for many Infectious Diseases
Pathogenic microorganisms utilize a variety of cell surface receptors to gain entry into host cells and to bypass the natural defense mechanisms. One of the most prominent receptors used in this fashion is the leukocyte adhesion receptor CD11b/c. This...  Read full blog post.

CD11b/CD18 and Neutrophil-Epithelial Interactions as Targets for Anti-Inflammatory Therapies
The beta-2 integrins, a family of four cell surface transmembrane glycoproteins expressed only on leukocytes, include CD11a/CD18, CD11b/CD18, CD11c/CD18, and CD11d/CD18. They consist of a common beta subunit (CD18) and homologous alpha subunits (CD11a...  Read full blog post.

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Recent Reviews

4
5
0
4
1
3
0
2
0
1
0

Verified Customer
09/17/2019
Application: IHC-P
Species: Human

Bioinformatics

Gene Symbol ITGAX