CD11c Products

Description

CD11c encodes the integrin alpha X chain protein. CD11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

Bioinformatics

Entrez	16411 Mouse 3687 Human
Uniprot	ABM86623.1 Human NP_000878 Human P20702 Human Q9QXH4 Mouse
Product By Gene ID	3687
Alternate Names	95 alpha chain 95 95, alpha subunit CD11 antigen-like family member C CD11c antigen CD11c CD11Cleu M5, alpha subunit integrin alpha-X integrin, alpha X (antigen CD11C (p150), alpha polypeptide) integrin, alpha X (complement component 3 receptor 4 subunit) Leu M5 Leukocyte adhesion glycoprotein p150 Leukocyte adhesion receptor p150 leukocyte surface antigen p150 myeloid membrane antigen, alpha subunit p150 95 integrin alpha chain SLEB6

Research Areas for CD11c

Find related products by research area and learn more about each of the different research areas below.

Dendritic Cell Markers
Signal Transduction

Related CD11c Blog Posts

Check out the latest blog posts on CD11c.

CD11b/CD18 and Neutrophil-Epithelial Interactions as Targets for Anti-Inflammatory Therapies The beta-2 integrins, a family of four cell surface transmembrane glycoproteins expressed only on leukocytes, include CD11a/CD18, CD11b/CD18, CD11c/CD18, and CD11d/CD18. They consist of a common beta subunit (CD18) and homologous alpha subunits (CD11a...    Read more.

Adhesion Receptor Molecule CD11b/c is the Point of Entry for many Infectious Diseases Pathogenic microorganisms utilize a variety of cell surface receptors to gain entry into host cells and to bypass the natural defense mechanisms. One of the most prominent receptors used in this fashion is the leukocyte adhesion receptor CD11b/c. This...    Read more.

CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a...    Read more.

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