Home » CCRL2/CRAM-A/B » CCRL2/CRAM-A/B Antibodies » CCRL2/CRAM-A/B Antibody (BZ5B8) [mFluor Violet 450 SE]
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CCRL2/CRAM-A/B Antibody (BZ5B8) [mFluor Violet 450 SE]

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CCRL2/CRAM-A/B Antibody (BZ5B8) [mFluor Violet 450 SE] [NBP3-11981MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an emission maximum of 445 nm.
CCRL2/CRAM-A/B Antibody (BZ5B8) [mFluor Violet 450 SE] [NBP3-11981MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IP, Func
Clone
BZ5B8
Clonality
Monoclonal
Host
Rat
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-11981AF350
Alexa Fluor 405
NBP3-11981AF405
Alexa Fluor 488
NBP3-11981AF488
Alexa Fluor 532
NBP3-11981AF532
Alexa Fluor 594
NBP3-11981AF594
Alexa Fluor 647
NBP3-11981AF647
Alexa Fluor 700
NBP3-11981AF700
Alexa Fluor 750
NBP3-11981AF750
Allophycocyanin
NBP3-11981APC
Biotin
NBP3-11981B
CoraFluor 1
NBP3-11981CL1
DyLight 350
NBP3-11981UV
DyLight 405
NBP3-11981V
DyLight 488
NBP3-11981G
DyLight 550
NBP3-11981R
DyLight 594
NBP3-11981DL594
DyLight 650
NBP3-11981C
DyLight 680
NBP3-11981FR
DyLight 755
NBP3-11981IR
FITC
NBP3-11981F
HRP
NBP3-11981H
Janelia Fluor 525
NBP3-11981JF525
Janelia Fluor 549
NBP3-11981JF549
Janelia Fluor 585
NBP3-11981JF585
Janelia Fluor 635
NBP3-11981JF635
Janelia Fluor 646
NBP3-11981JF646
Janelia Fluor 669
NBP3-11981JF669
PE
NBP3-11981PE
PerCP
NBP3-11981PCP
Unconjugated
NBP3-11981-0.2mg
mFluor Violet 500 SE
NBP3-11981MFV500
mFluor Violet 610 SE
NBP3-11981MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-11981-0.2mg
Azide and BSA Free
NBP3-11981-0.2mg
Azide and BSA Free
NBP3-11981-0.025mg
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CCRL2/CRAM-A/B Antibody (BZ5B8) [mFluor Violet 450 SE] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was raised by immunising Wistar Furth rats with the mCCRL2/CRAM-A/B peptide/KLH conjugate. The immunizing amino-terminal mCCRL2/CRAM-A/B peptide with the sequence NH2-MDNYTVAPDDEYDVLILDDYLDNSC-COOH, corresponding to residues 1-24 of mCCRL2/CRAM-A/B, with a nonnative carboxyl-terminal cysteine to facilitate conjugation to keyhole limpet hemocyanin (KLH).
Specificity
This antibody is specific for murine CCRL2/CRAM-A/B (formerly known as L-CCR), which is expressed on mast cells, activated macrophages, and endothelial cells. This receptor binds the leukocyte chemoattractant chemerin without triggering classical GPCR signaling, providing a specific mechanism for local enrichment of chemerin at inflammatory sites. CCRL2/CRAM-A/B presents active chemerin to leukocytes expressing the chemoattractant receptor CMKLR1/Chemr23. Chemerin can block anti-CCRL2/CRAM-A/B antibody binding.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
CCRL2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for CCRL2/CRAM-A/B Antibody (BZ5B8) [mFluor Violet 450 SE]

  • ACKR5
  • C-C chemokine receptor-like 2
  • CCR11
  • CCR6
  • CCRL2
  • CCRL2/CRAM-A/B
  • chemokine (C-C motif) receptor-like 2
  • Chemokine receptor CCR11
  • Chemokine receptor X
  • CKRX
  • CKRXMGC116710
  • CRAM
  • CRAMA
  • CRAM-A
  • CRAMB
  • CRAM-B
  • FLJ55815
  • HCR
  • HCRMGC34104
  • Putative MCP-1 chemokine receptor

Background

CCRL2 encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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(100 Publications)
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CCRL2/CRAM-A/B
Antibody (BZ5B8) [mFl ...
NBP3-11981MFV450
CCRL2/CRAM-A/B Antibody (BZ5B8) [mFluor Violet 450 SE]
Species: Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IP, Func

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Bioinformatics

Gene Symbol CCRL2