Home » CCRL2/CRAM-A/B » CCRL2/CRAM-A/B Antibodies » CCRL2/CRAM-A/B Antibody (BZ2E3) - Azide and BSA Free
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CCRL2/CRAM-A/B Antibody (BZ2E3) - Azide and BSA Free

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IP, Func
Clone
BZ2E3
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-11983AF350
Alexa Fluor 405
NBP3-11983AF405
Alexa Fluor 488
NBP3-11983AF488
Alexa Fluor 532
NBP3-11983AF532
Alexa Fluor 594
NBP3-11983AF594
Alexa Fluor 647
NBP3-11983AF647
Alexa Fluor 700
NBP3-11983AF700
Alexa Fluor 750
NBP3-11983AF750
Allophycocyanin
NBP3-11983APC
Biotin
NBP3-11983B
CoraFluor 1
NBP3-11983CL1
DyLight 350
NBP3-11983UV
DyLight 405
NBP3-11983V
DyLight 488
NBP3-11983G
DyLight 550
NBP3-11983R
DyLight 594
NBP3-11983DL594
DyLight 650
NBP3-11983C
DyLight 680
NBP3-11983FR
DyLight 755
NBP3-11983IR
FITC
NBP3-11983F
HRP
NBP3-11983H
Janelia Fluor 525
NBP3-11983JF525
Janelia Fluor 549
NBP3-11983JF549
Janelia Fluor 585
NBP3-11983JF585
Janelia Fluor 635
NBP3-11983JF635
Janelia Fluor 646
NBP3-11983JF646
Janelia Fluor 669
NBP3-11983JF669
PE
NBP3-11983PE
PerCP
NBP3-11983PCP
mFluor Violet 450 SE
NBP3-11983MFV450
mFluor Violet 500 SE
NBP3-11983MFV500
mFluor Violet 610 SE
NBP3-11983MFV610
View Available Formulations
Catalog# & Formulation Size Price
Azide and BSA Free
NBP3-11983-0.025mg
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CCRL2/CRAM-A/B Antibody (BZ2E3) - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was raised by immunising Wistar Furth rats with the mCCRL2/CRAM-A/B peptide/KLH conjugate. The immunizing amino-terminal mCCRL2/CRAM-A/B peptide with the sequence NH2-MDNYTVAPDDEYDVLILDDYLDNSC-COOH, corresponding to residues 1-24 of mCCRL2/CRAM-A/B, with a nonnative carboxyl-terminal cysteine to facilitate conjugation to keyhole limpet hemocyanin (KLH).
Specificity
This antibody is specific for murine CCRL2/CRAM-A/B (formerly known as L-CCR), which is expressed on mast cells, activated macrophages, and endothelial cells. This receptor binds the leukocyte chemoattractant chemerin without triggering classical GPCR signaling, providing a specific mechanism for local enrichment of chemerin at inflammatory sites. CCRL2/CRAM-A/B presents active chemerin to leukocytes expressing the chemoattractant receptor CMKLR1/Chemr23. Chemerin can block anti-CCRL2/CRAM-A/B antibody binding.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
CCRL2
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Buffer
PBS
Preservative
0.02% Proclin 300
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for CCRL2/CRAM-A/B Antibody (BZ2E3) - Azide and BSA Free

  • ACKR5
  • C-C chemokine receptor-like 2
  • CCR11
  • CCR6
  • CCRL2
  • CCRL2/CRAM-A/B
  • chemokine (C-C motif) receptor-like 2
  • Chemokine receptor CCR11
  • Chemokine receptor X
  • CKRX
  • CKRXMGC116710
  • CRAM
  • CRAMA
  • CRAM-A
  • CRAMB
  • CRAM-B
  • FLJ55815
  • HCR
  • HCRMGC34104
  • Putative MCP-1 chemokine receptor

Background

CCRL2 encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CCRL2/CRAM-A/B
Antibody (BZ2E3) - Az ...
NBP3-11983
CCRL2/CRAM-A/B Antibody (BZ2E3) - Azide and BSA Free
Species: Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IP, Func

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Bioinformatics

Gene Symbol CCRL2