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CCR8 Antibody (191704) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
191704
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 585

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CCR8 Antibody (191704) [Janelia Fluor® 585] Summary

Additional Information
Clone 191704 was used by HLDA to establish CD designation
Immunogen
BaF3 mouse pro-B cell line transfected with human CCR8
Met1-Leu355
Accession # P51685
Specificity
Detects human CCR8. Neutralizes the bioactivity of human CCR8 and specifically stains human CCR8-transfected cell lines but not with the parent cell lines.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
CCR8
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CCR8 Antibody (191704) [Janelia Fluor® 585]

  • CC chemokine receptor 8
  • C-C CKR-8
  • CC-chemokine receptor chemr1
  • CC-CKR-8
  • CCR8
  • CCR-8
  • CD198
  • CDw198 antigen
  • CDw198
  • chemokine (C-C motif) receptor 8
  • chemokine (C-C) receptor 8
  • chemokine (C-C) receptor-like 2
  • Chemokine receptor-like 1
  • ChemR1
  • CKRL1
  • CKR-L1
  • CKRL1MGC129966
  • CMKBR8MGC129973
  • CMKBRL2C-C chemokine receptor type 8
  • CY6
  • GPRCL1
  • GPRCY6
  • GPR-CY6
  • TER-1
  • TER1CC chemokine receptor CHEMR1

Background

CKR8/CCR8, or C-C chemokine receptor type 8, is a G protein-coupled, seven-transmembrane domain receptor protein. Chemokines are key molecules in directing leukocyte migration toward sites of inflammation. The human C-C chemokine I-309 is a monocyte chemoattractant and inhibits apoptosis in thymic cell lines. It has been found that CKR8/CCR8 is a receptor for chemokines SCYA1/I-309, SCYA4/MIP-1-beta, and SCYA17/TARC (1-3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional CCR8 Products

Array FAB1429JF585

Research Areas for CCR8 Antibody (FAB1429JF585)

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Bioinformatics

Gene Symbol CCR8