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CCR5 Antibody (CTC5) [Allophycocyanin]

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 (2 Reviews)
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Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3e Alexa Fluor® 405-conjugated Monoclonal Antibody (Catalog # FAB100V) and either (A) Mouse Anti-Human/Mouse/Rat CCR5 APC-conjugated Monoclonal Antibody (Catalog # FAB1802A) or (B) Mouse IgG1Allophycocyanin Isotype Control (Catalog # IC002A). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3e Alexa Fluor® 405-conjugated Monoclonal Antibody (Catalog # FAB100V) and either (A) Mouse Anti-Human/Mouse/Rat CCR5 ...read more
Mouse splenocytes treated with anti-CD3, anti-CD28, 5 ng/mL Recombinant Mouse IL-12 (Catalog # 419-ML) and 10 µg/mL Goat Anti-Mouse IL-4 Poly-clonal Antibody (Catalog # AB-404-NA) to induce Th1 development for 3 days ...read more
Rat splenocytes were stained with Mouse Anti-Human/Mouse/Rat CCR5 APC-conjugated Monoclonal Antibody (Catalog # FAB1802A) and Anti-Rat CD3 PE-conjugated Antibody. Quadrant markers were set based on control antibody ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow
Clone
CTC5
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1802U-100UG
Alexa Fluor 405
FAB1802V-100UG
Alexa Fluor 488
FAB1802G-100UG
Alexa Fluor 532
FAB1802X
Alexa Fluor 594
FAB1802T-100UG
Alexa Fluor 647
FAB1802R-100UG
Alexa Fluor 700
FAB1802N-100UG
Alexa Fluor 750
FAB1802S-100UG
Allophycocyanin
FAB1802A-100
Allophycocyanin/Cy7
FAB1802APCCY7
Biotin
FAB1802B
CoraFluor 1
FAB1802CL1
DyLight 350
FAB1802D
DyLight 405
FAB1802E
DyLight 488
FAB1802K
DyLight 550
FAB1802L
DyLight 594
FAB1802M
DyLight 650
FAB1802W
DyLight 680
FAB1802Y
DyLight 755
FAB1802Z
HRP
FAB1802H
Janelia Fluor 525
FAB1802JF525
Janelia Fluor 549
FAB1802I
Janelia Fluor 646
FAB1802J
Janelia Fluor 669
FAB1802JF669
PE/Atto594
FAB1802PEATT594
PE/Cy5.5
FAB1802PECY55
PE/Cy7
FAB1802PECY7
PerCP
FAB1802C
Phycoerythrin
FAB1802P-100
Phycoerythrin
FAB1802P-025
Unconjugated
MAB1802-100
mFluor Violet 450 SE
FAB1802MFV450
mFluor Violet 500 SE
FAB1802MFV500
mFluor Violet 610 SE
FAB1802MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1802-100
Carrier Free
FAB1802P-025
Carrier Free
FAB1802P-100
Carrier Free
MAB1802-100
Carrier Free
FAB1802A-100
Carrier Free
MAB1802-SP
Carrier Free
FAB1802V-100UG
Carrier Free
FAB1802U-100UG
Carrier Free
FAB1802T-100UG
Carrier Free
FAB1802S-100UG
Carrier Free
FAB1802R-100UG
Carrier Free
FAB1802N-100UG
Carrier Free
FAB1802G-100UG
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CCR5 Antibody (CTC5) [Allophycocyanin] Summary

Immunogen
CHO Chinese hamster ovary cell line transfected with human CCR5
Specificity
Detects human CCR5 in Western blots. For additional information regarding epitope specificity for this antibody and other R&D Systems anti‑human CCR5 antibodies, see Reference 1.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CCR5
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 2 Reviews rated 5
using
FAB1802A in the following application:
Publications
Read Publications using
FAB1802A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR5 Antibody (CTC5) [Allophycocyanin]

  • C-C CKR-5
  • C-C motif chemokine receptor 5 A159A
  • CCCKR5
  • CC-CKR-5FLJ78003
  • CCR5
  • CCR-5
  • CD195 antigen
  • CD195
  • chemokine (C-C motif) receptor 5
  • chemokine receptor CCR5
  • chemr13
  • CKR5
  • CKR-5
  • HIV-1 fusion coreceptor
  • IDDM22CMKBR5C-C chemokine receptor type 5

Background

CCR5 is a G protein-linked seven transmembrane domain chemokine receptor. CCR5 serves as a receptor for several chemokines including MIP-1 alpha , MIP-1 beta , MCP-2, and RANTES. It also functions as a coreceptor for Macrophage Tropic HIV-1 infection.

  1. Lee, B. et al. (1999) J. Biol. Chem. 274:9617.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Flow Cytometry CXCR3 Antibody (49801) [Unconjugated]
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Publications for CCR5 Antibody (FAB1802A)(10)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Flow Cytometry, ICC.


Filter By Application
Flow Cytometry
(7)
ICC
(1)
All Applications
Filter By Species
Human
(8)
All Species
Showing Publications 1 - 10 of 10.
Publications using FAB1802A Applications Species
Xuanmao Jiao, Min Wang, Zhao Zhang, Zhiping Li, Dong Ni, Anthony W. Ashton et al. Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy Breast Cancer Research 1/23/2021 [PMID: 33485378]
JM Laufer, MA Hauser, I Kindinger, V Purvanov, A Pauli, DF Legler Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation Cell Rep, 2019-10-22;29(4):995-1009.e6. 2019-10-22 [PMID: 31644919] (Flow Cytometry, Human) Flow Cytometry Human
X Jiao, MA Velasco-Ve, M Wang, Z Li, H Rui, AR Peck, JE Korkola, X Chen, S Xu, JB DuHadaway, S Guerrero-R, S Addya, D Sicoli, Z Mu, G Zhang, A Stucky, X Zhang, M Cristofani, A Fatatis, JW Gray, JF Zhong, GC Prendergas, RG Pestell CCR5 governs DNA damage and breast cancer stem cell expansion Cancer Res., 2018-01-22;0(0):. 2018-01-22 [PMID: 29358169] (Flow Cytometry, Human) Flow Cytometry Human
CIB1 and CIB2 are HIV-1 helper factors involved in viral entry Sci Rep, 2016-08-04;6(0):30927. 2016-08-04 [PMID: 27489023] (Flow Cytometry, Human) Flow Cytometry Human
Sicoli D, Jiao X, Ju X, Velasco-Velazquez M, Ertel A, Addya S, Li Z, Ando S, Fatatis A, Paudyal B, Cristofanilli M, Thakur M, Lisanti M, Pestell R CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines. Cancer Res, 2014-12-01;74(23):7103-14. 2014-12-01 [PMID: 25452256] (Flow Cytometry, Human) Flow Cytometry Human
Engin Baturcam, Jehad Abubaker, Ali Tiss, Mohamed Abu-Farha, Abdelkrim Khadir, Fahad Al-Ghimlas et al. Physical Exercise Reduces the Expression of RANTES and Its CCR5 Receptor in the Adipose Tissue of Obese Humans Mediators of Inflammation 4/17/2014 [PMID: 24895488]
Morandi , Fabio, Di Carlo , Emma, Ferrone , Soldano, Petretto , Andrea, Pistoia , Vito, Airoldi , Irma IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol, 2014-02-19;192(6):2634-42. 2014-02-19 [PMID: 24554774] (Flow Cytometry, Human) Flow Cytometry Human
Velasco-Velazquez M, Jiao X, De la Fuente M, Pestell T, Ertel A, Lisanti M, Pestell R CCR5 antagonist blocks metastasis of basal breast cancer cells. Cancer Res, 2012-05-25;72(15):3839-50. 2012-05-25 [PMID: 22637726] (Flow Cytometry, Human) Flow Cytometry Human
Prendergast A, Prado JG, Kang YH, Chen F, Riddell LA, Luzzi G, Goulder P, Klenerman P HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells. AIDS, 2010-02-20;24(4):491-502. 2010-02-20 [PMID: 20071976] (Flow Cytometry, Human) Flow Cytometry Human
Bayry J, Triebel F, Kaveri SV, Tough DF Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J. Immunol., 2007-04-01;178(7):4184-93. 2007-04-01 [PMID: 17371975] (ICC, Human) ICC Human

Reviews for CCR5 Antibody (FAB1802A) (2) 52

Average Rating: 5
(Based on 2 reviews)
We have 2 reviews tested in 1 species: Human.

Reviews using FAB1802A:
Filter by Applications
Flow
(2)
All Applications
Filter by Species
Human
(2)
All Species
Images Ratings Applications Species Date Details
  5
reviewed by:
Verified Customer
 Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID:22637726
SpeciesHuman
  5
reviewed by:
Verified Customer
 Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 22637726
SpeciesHuman

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Recent Reviews

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 Verified Customer
01/21/2015
Application: Flow
Species: Human
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 Verified Customer
01/21/2015
Application: Flow
Species: Human
read this review

Bioinformatics

Gene Symbol CCR5