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CCL8/MCP-2 Antibody (35509.11) [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC
Clone
35509.11
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB120-10391AF350
Alexa Fluor 405
NB120-10391AF405
Alexa Fluor 488
NB120-10391AF488
Alexa Fluor 532
NB120-10391AF532
Alexa Fluor 594
NB120-10391AF594
Alexa Fluor 647
NB120-10391AF647
Alexa Fluor 700
NB120-10391AF700
Alexa Fluor 750
NB120-10391AF750
Biotin
NB120-10391B
DyLight 350
NB120-10391UV
DyLight 405
NB120-10391V
DyLight 488
NB120-10391G
DyLight 550
NB120-10391R
DyLight 594
NB120-10391DL594
DyLight 650
NB120-10391C
DyLight 680
NB120-10391FR
DyLight 755
NB120-10391IR
FITC
NB120-10391F
Janelia Fluor 549
NB120-10391JF549
Janelia Fluor 646
NB120-10391JF646
Unconjugated
NB120-10391
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CCL8/MCP-2 Antibody (35509.11) [HRP] Summary

Immunogen
Recombinant human monocyte chemotactic protein 2 (MCP2), expressed in E. coli.
Localization
Secreted
Specificity
By ELISA, this antibody shows cross-reactivity with recombinant human MCP1 and recombinat mouse MIP1 alpha. In addition, it does not cross-react with other chemokines tested: rmC10, rhENA78, rhGRO alpha, rhGRO beta, rhGRO gamma, rmJE, rhI309, and rhIL8.

This antibody neutralizes the biological activity of recombinant human MCP-2. Shows <20% cross-reactivity with recombinant human MCP-1 and recombinant mouse MIP-1a.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CCL8
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CCL8/MCP-2 Antibody (35509.11) [HRP]

  • C-C motif chemokine 8
  • CCL8
  • chemokine (C-C motif) ligand 8
  • HC14
  • MCP2
  • MCP-2
  • member 8 (monocyte chemotactic protein 2)
  • monocyte chemoattractant protein 2
  • SCYA10
  • small-inducible cytokine A8

Background

MCP2 and MCP3 are two recently identified monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and MCP3 are members of the C-C family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. MCP3 also shares 58% amino acid identity with MCP2. Similarly to other C-C chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CCL8
Entrez