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Canine IL-17A DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity CaSpecies Glossary
Applications ELISA
Conjugate
Biotin

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Canine IL-17A DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
IL17A

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY5848.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Canine IL-17A DuoSet ELISA, 15 Plate

  • CTLA8
  • CTLA-8
  • CTLA8cytotoxic T-lymphocyte-associated serine esterase 8
  • Cytotoxic T-lymphocyte-associated antigen 8
  • IL17
  • IL-17
  • IL17A
  • IL-17A
  • IL-17Acytotoxic T-lymphocyte-associated protein 8
  • IL-17CTLA-8
  • IL17interleukin-17A
  • interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
  • interleukin 17A

Background

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

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Publications for IL-17/IL-17A (DY5848)(7)

We have publications tested in 1 confirmed species: Canine.


Filter By Application
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Filter By Species
Canine
(7)
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Showing Publications 1 - 7 of 7.
Publications using DY5848 Applications Species
M Pelst, C Höbart, H de Rooster, B Devriendt, E Cox Immortalised canine buccal epithelial cells' CXCL8 secretion is affected by allergen extracts, Toll-like receptor ligands, IL-17A and calcitriol Veterinary research, 2022-09-13;53(1):72. 2022-09-13 [PMID: 36100942] (Canine) Canine
S Kim, YS Hyun, HT Park, MK Shin, HS Yoo Mycobacterium intracellulare induces a Th17 immune response via M1-like macrophage polarization in canine peripheral blood mononuclear cells Scientific Reports, 2022-07-12;12(1):11818. 2022-07-12 [PMID: 35821058] (Canine) Canine
H Desai, M Marathe, V Potdar, P Tiwari, A Joshi, SR Kadam, AR Joshi, A Kulkarni, V Bhosale, A Hadambar, B Lodhiya, V Udupa, D Behera, SS Chaudhari, S Das, M Bajpai, N Gowda, PS Iyer An inhibitor of RORgamma for chronic pulmonary obstructive disease treatment Scientific Reports, 2022-05-24;12(1):8744. 2022-05-24 [PMID: 35610240] (Canine) Canine
JP Bragato, GT Rebech, JH Freitas, MOD Santos, SF Costa, FR Eugênio, PSPD Santos, VMF de Lima miRNA-21 regulates CD69 and IL-10 expression in canine leishmaniasis PLoS ONE, 2022-03-24;17(3):e0265192. 2022-03-24 [PMID: 35324917] (Canine) Canine
JK Abbott, SK Chan, M MacBeth, JL Crooks, C Hancock, V Knight, EW Gelfand Fluctuations in quality of life and immune responses during intravenous immunoglobulin infusion cycles PLoS ONE, 2022-03-22;17(3):e0265852. 2022-03-22 [PMID: 35316278] (Canine) Canine
JK Bujak, IM Szopa, R Pingwara, O Kruczyk, N Krzemi?ska, J Mucha, K Majchrzak- The Expression of Selected Factors Related to T Lymphocyte Activity in Canine Mammary Tumors Int J Mol Sci, 2020-03-26;21(7):. 2020-03-26 [PMID: 32225066] (Canine) Canine
M Pujol, C Borie, M Montoya, A Ferreira, R Vernal Brucella canis induces canine CD4+ T cells multi-cytokine Th1/Th17 production via dendritic cell activation Comp. Immunol. Microbiol. Infect. Dis., 2018-11-30;62(0):68-75. 2018-11-30 [PMID: 30711049] (Canine) Canine

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Product General Protocols

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FAQs for IL-17/IL-17A (DY5848). (Showing 1 - 2 of 2 FAQs).

  1. I want to stain some T cell subsets (Th17 and Th1), do you have antibodies for that? I need for flow cytometer in sheep or goat.
    • Unfortunately, we have neither a CD4 antibody nor an IL-17 antibody that has been validated in sheep or goat, although if you would like to try one you would again be eligible for our Innovators Reward Program. Please contact us at innovators@novusbio.com with any questions regarding this program.
  2. I'm looking to establish an ELISA for IL-17 and want your recommendation on which antibody pairs to buy. Least expensive ones, please. Also, I'd like the detection antibody to be fluorescently labeled.
    • Thank you for your patience while I reviewed our ELISA validated products for IL17. I was not sure what species you were going to be investigating, so I looked up our data for the human protein. If this is incorrect, just let me know and I can look up products for the species you will be working with. As for antibody pairs, we only had one set that have been tested together: Capture: NBP2-22531 Detection: NBP2-22532. The detection product is only available currently with a biotin conjugate. We can however offer custom conjugation for this product to any of our available conjugates. Please see the this link to see the available fluors. The typical fee for custom conjugation is usually about $80 additional. Once you know which fluor you would like, I can provide you with a quote. We do also offer several ELISA kits for this target (they typically employ HRP or Biotin detection systems, so I am not sure if they will work for your needs).
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Bioinformatics

Gene Symbol IL17A