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BRIP1/FANCJ Antibody (27F4)

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Western Blot: BRIP1/FANCJ Antibody (27F4) [NBP3-26474] - Positive Western Blot detected in: MCF7 whole cell lysate, HEPG2 whole cell lysate. All lanes: BRIP1/FANCJ Antibody at 1: 1000 Secondary: Goat polyclonal to ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
27F4
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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BRIP1/FANCJ Antibody (27F4) Summary

Additional Information
Recombinant monoclonal antibody expressed in HEK293F cells
Immunogen
A synthesized peptide derived from Human BRIP1/FANCJ [UniProt Q9BX63]
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
BRIP1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at -20 to -70C. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl and 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for BRIP1/FANCJ Antibody (27F4)

  • ATP-dependent RNA helicase BRIP1
  • BACH1
  • BACH1BRCA1/BRCA2-associated helicase 1
  • BRCA1 interacting protein C-terminal helicase 1
  • BRCA1-associated C-terminal helicase 1
  • BRCA1-binding helicase-like protein BACH1
  • BRCA1-interacting protein 1
  • BRCA1-interacting protein C-terminal helicase 1
  • BRIP1
  • EC 3.6.1
  • EC 3.6.4.13
  • FACJ
  • FANCJ
  • FANCJFanconi anemia group J protein
  • FLJ90232
  • MGC126521
  • MGC126523
  • OF
  • Protein FACJ

Background

The Fanconi anemia group subunit J protein (FANCJ), also called BRIP1 or BACH1, is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. Defects in FANCJ cause the autosomal recessive disorder, Fanconi anemia. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation.

FANCG antibodies are useful for DNA repair studies and cell cycle research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol BRIP1