FANCM Antibody (CV5.1) - BSA Free

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IHC-P, WB.

Showing Publications 1 - 6 of 6.

Publications using NBP2-50418	Applications	Species
Dzaparidze G, Kazachonok D, Gvozdkov A et al. Diagnostic significance of stromal changes in biopsies of prostate adenocarcinoma Pathology, research and practice 2021-04-08 [PMID: 33857855]
Brannvoll A, Xue X, Kwon Y et al. The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells Cell Rep 2020-07-07 [PMID: 32640219] (WB, Human)	WB	Human
Dzaparidze G, Anion E, Laan M, Minajeva A The decline of FANCM immunohistochemical expression in prostate cancer stroma correlates with the grade group Pathol. Int. 2020-05-28 [PMID: 32462745] (IHC-P, Human)	IHC-P	Human
Lu R, O'Rourke J, Sobinoff A et al. The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT) Nat Commun 2019-05-28 [PMID: 31138797] (WB, WB, Human)	WB, WB	Human
Kasak L, Punab M, Nagirnaja L et al. Bi-allelic Recessive Loss-of-Function Variants in FANCM Cause Non-obstructive Azoospermia Am. J. Hum. Genet. 2018-08-02 [PMID: 30075111] (IHC-P, Human)	IHC-P	Human
Fouquet B, Pawlikowska P, Caburet S et al. A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency. Elife 2017-12-12 [PMID: 29231814] (IHC-P, Human)	IHC-P	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Robert Lu	WB	Human	10/07/2020	View Summary Application Western Blot Sample Tested Hela whole cell lysate Species Human Lot CRT/20/13 Comments Comments Cells were lysed using RIPA buffer supplemented with protease inhibitor cocktail. 20ug protein per lane. PVDF membrane was blocked with 5% milk in PBST. Diluted in 0.5% milk in PBST. Band signal requires requires femtomolar ECL reagent in order to detect in under 3 minutes.

Array NBP2-50418

• FANCM Antibodies
• FANCM Protein