BMPR-II Antibody (3F6) - BSA Free

BMPR2 encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NBP2-37624	Applications	Species
Toyama T, Kudryashova TV, Ichihara A et al. GATA6 coordinates cross-talk between BMP10 and oxidative stress axis in pulmonary arterial hypertension Scientific reports 2023-04-22 [PMID: 37087509] (WB, Human)	WB	Human

Array NBP2-37624

• BMPR-II Antibodies
• BMPR-II ELISA Kits
• BMPR-II Lysate
• BMPR-II Proteins
• BMPR-II Proteins and Enzyme