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BIN1 Antibody (1H1)

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Western Blot: BIN1 Antibody (1H1) [H00000274-M01] - Analysis of BIN1 expression in transfected 293T cell line by BIN1 monoclonal antibody (M01), clone 1H1.Lane 1: BIN1 transfected lysate(53 KDa).Lane 2: Non-transfected ...read more
Western Blot: BIN1 Antibody (1H1) [H00000274-M01] - BIN1 monoclonal antibody (M01), clone 1H1 Analysis of BIN1 expression in Hela S3 NE.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1H1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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BIN1 Antibody (1H1) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
BIN1 (NP_004296, 355 a.a. ~ 454 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Specificity
BIN1 - bridging integrator 1
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
BIN1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BIN1 Antibody (1H1)

  • AMPH2
  • Amphiphysin II
  • Amphiphysin-like protein
  • AMPHLDKFZp547F068
  • box dependant MYC interacting protein 1
  • bridging integrator 1Box-dependent myc-interacting protein 1
  • MGC10367
  • myc box-dependent-interacting protein 1
  • SH3P9

Background

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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H00000274-M01
Species: Hu
Applications: WB, ELISA

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for BIN1 Antibody (H00000274-M01) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol BIN1
Entrez
OMIM
Uniprot