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B7-H2/ICOSLG Antibody (987602) [DyLight 350]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
987602
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB10083U-100UG
Alexa Fluor 405
FAB10083V-100UG
Alexa Fluor 488
FAB10083G-100UG
Alexa Fluor 532
FAB10083X
Alexa Fluor 594
FAB10083T-100UG
Alexa Fluor 647
FAB10083R-100UG
Alexa Fluor 700
FAB10083N-100UG
Alexa Fluor 750
FAB10083S-100UG
Allophycocyanin
FAB10083A
Allophycocyanin/Cy7
FAB10083APCCY7
Biotin
FAB10083B
DyLight 405
FAB10083E
DyLight 488
FAB10083K
DyLight 550
FAB10083L
DyLight 594
FAB10083M
DyLight 650
FAB10083W
DyLight 680
FAB10083Y
DyLight 755
FAB10083Z
FITC
FAB10083F
HRP
FAB10083H
Janelia Fluor 549
FAB10083I
Janelia Fluor 646
FAB10083J
PE
FAB10083P
PE/Atto594
FAB10083PEATT594
PE/Cy5.5
FAB10083PECY55
PE/Cy7
FAB10083PECY7
PerCP
FAB10083C
Unconjugated
MAB10083-100
mFluor Violet 450 SE
FAB10083MFV450
mFluor Violet 500 SE
FAB10083MFV500
mFluor Violet 610 SE
FAB10083MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB10083-100
Carrier Free
MAB10083-100
Carrier Free
MAB10083-SP
Carrier Free
FAB10083V-100UG
Carrier Free
FAB10083U-100UG
Carrier Free
FAB10083T-100UG
Carrier Free
FAB10083S-100UG
Carrier Free
FAB10083R-100UG
Carrier Free
FAB10083N-100UG
Carrier Free
FAB10083G-100UG
100% Guarantee on every product

B7-H2/ICOSLG Antibody (987602) [DyLight 350] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse B7-H2
Met1-Lys279
Accession # Q9JHJ8
Specificity
Detects mouse B7-H2 in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for B7-H2/ICOSLG Antibody (987602) [DyLight 350]

  • B7H2
  • B7-H2
  • B7H2B7 homolog 2
  • B7-H2B7-related protein 1
  • B7RP-1
  • B7RP1B7-like protein Gl50
  • B7RP-1LICOS
  • CD275 antigen
  • CD275
  • GL50
  • GL50transmembrane protein B7-H2 ICOS ligand
  • ICOSL
  • ICOS-L
  • ICOSLG
  • inducible T-cell co-stimulator ligand
  • KIAA0653ICOS ligand

Background

B7-RP1 is a 40 kD protein, also known as ICOS ligand, B7-H2, and B7h. It has recently been clustered as CD275. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells and macrophages. The expression of this antigen is increased by TNF- alpha stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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B7-H2/ICOSLG
Antibody (987602) [Dy ...
FAB10083D
B7-H2/ICOSLG Antibody (987602) [DyLight 350]
Species: Mu
Applications: Flow, B/N, CyTOF-ready

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