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B7-H2/ICOSLG Antibody (136726) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
136726
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB165U-100UG
Alexa Fluor 405
FAB165V-100UG
Alexa Fluor 488
FAB165G-100UG
Alexa Fluor 532
FAB165X
Alexa Fluor 594
FAB165T-100UG
Alexa Fluor 647
FAB165R-100UG
Alexa Fluor 700
FAB165N-100UG
Alexa Fluor 750
FAB165S-100UG
Allophycocyanin
FAB165A
Allophycocyanin/Cy7
FAB165APCCY7
CoraFluor 1
FAB165CL1
DyLight 350
FAB165D
DyLight 405
FAB165E
DyLight 488
FAB165K
DyLight 550
FAB165L
DyLight 594
FAB165M
DyLight 650
FAB165W
DyLight 680
FAB165Y
DyLight 755
FAB165Z
FITC
FAB165F
HRP
FAB165H
Janelia Fluor 525
FAB165JF525
Janelia Fluor 549
FAB165I
Janelia Fluor 585
FAB165JF585
Janelia Fluor 635
FAB165JF635
Janelia Fluor 646
FAB165J
Janelia Fluor 669
FAB165JF669
PE/Atto594
FAB165PEATT594
PE/Cy5.5
FAB165PECY55
PE/Cy7
FAB165PECY7
PerCP (Peridinin-chlorophyll Protein Complex)
FAB165C
Phycoerythrin
FAB165P
Unconjugated
MAB165-100
mFluor Violet 450 SE
FAB165MFV450
mFluor Violet 500 SE
FAB165MFV500
mFluor Violet 610 SE
FAB165MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB165-100
Carrier Free
FAB165A
Carrier Free
FAB165C
Carrier Free
FAB165P
Carrier Free
MAB165-SP
Carrier Free
MAB165-100
Carrier Free
MAB165-500
Carrier Free
FAB165V-100UG
Carrier Free
FAB165U-100UG
Carrier Free
FAB165T-100UG
Carrier Free
FAB165S-100UG
Carrier Free
FAB165R-100UG
Carrier Free
FAB165N-100UG
Carrier Free
FAB165G-100UG
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B7-H2/ICOSLG Antibody (136726) [Biotin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human B7-H2
Asp19-Ser258
Accession # O75144
Specificity
Detects human B7-H2 in direct ELISAs. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) B7-1, rhB7-2, rhB7-H1, rhB7-H3, or recombinant mouse B7-H2 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ICOSLG
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for B7-H2/ICOSLG Antibody (136726) [Biotin]

  • B7H2
  • B7-H2
  • B7H2B7 homolog 2
  • B7-H2B7-related protein 1
  • B7RP-1
  • B7RP1B7-like protein Gl50
  • B7RP-1LICOS
  • CD275 antigen
  • CD275
  • GL50
  • GL50transmembrane protein B7-H2 ICOS ligand
  • ICOSL
  • ICOS-L
  • ICOSLG
  • inducible T-cell co-stimulator ligand
  • KIAA0653ICOS ligand

Background

B7-RP1 is a 40 kD protein, also known as ICOS ligand, B7-H2, and B7h. It has recently been clustered as CD275. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells and macrophages. The expression of this antigen is increased by TNF- alpha stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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B7-H2/ICOSLG
Antibody (136726) [Bi
FAB165B
B7-H2/ICOSLG Antibody (136726) [Biotin]
Species: Hu
Applications: Flow, B/N, CyTOF-ready

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Bioinformatics

Gene Symbol ICOSLG