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APCDD1 Antibody - BSA Free

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Genetic Strategies: Knockdown Validated: APCDD1 Antibody - BSA Free [NB110-92756] - APCDD1 knockdown potently (C) inhibited cell proliferation. Error bars represent mean +/- SD of three replicates (*P < 0.05, **P ...read more
Western Blot: APCDD1 Antibody [NB110-92756] - Detection of APCDD1 in human heart lysate

Product Details

Summary
Reactivity Hu, Mu, Ch, ReSpecies Glossary
Applications WB, KD
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.3 mg/ml
Validated by:
     

Genetic Strategies

   

Order Details

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APCDD1 Antibody - BSA Free Summary

Immunogen
Synthetic peptide made to an internal portion of human APCDD1 (within residues 400-500). [Swiss-Prot# Q8J025]
Localization
Membrane.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
APCDD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Knockdown Validated
  • Western Blot 0.5 ug/ml
Application Notes
This APCDD1 antibody is useful for Western blot, where a band is seen ~58 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
Human Heart Whole Tissue Lysate (Adult Whole Normal)
Control Peptide
APCDD1 Peptide (NB110-92756PEP)
Publications
Read Publications using
NB110-92756 in the following applications:

  • WB
    2 publications

Reactivity Notes

Turtle.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 30% Glycerol
Preservative
0.1% Sodium Azide
Concentration
1.3 mg/ml
Purity
Immunogen affinity purified

Alternate Names for APCDD1 Antibody - BSA Free

  • Adenomatosis polyposis coli down-regulated 1 protein
  • adenomatosis polyposis coli down-regulated 1
  • APC Down Regulated 1
  • APCDD1
  • B7323
  • DRAPC1
  • HYPT1
  • protein APCDD1

Background

APCDD1 (Drapc1) is a novel protein that has been shown to be a target of Wnt/beta-catenin signaling pathway in cancer cell lines. APCDD1 is overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1-mutated Wilms tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for APCDD1 Antibody (NB110-92756)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: WB.


Filter By Application
WB
(2)
All Applications
Filter By Species
Human
(1)
Mouse
(1)
All Species
Showing Publications 1 - 2 of 2.
Publications using NB110-92756 Applications Species
Ding W, Li X, Zhang J et al. Adaptive Functions of Structural Variants in Human Brain Development bioRxiv 2023-09-26 (WB, Mouse) WB Mouse
Lin L, Huang M, Shi X et al. Super-enhancer-associated MEIS1 promotes transcriptional dysregulation in Ewing sarcoma in co-operation with EWS-FLI1. Nucleic Acids Res. 2018-11-28 [PMID: 30496486] (WB, Human) WB Human

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Product General Protocols

View specific protocols for APCDD1 Antibody (NB110-92756): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for APCDD1 Antibody (NB110-92756) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol APCDD1