Apc1 Antibody - BSA Free

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 application: FLOW.

Showing Publication 1 - 1 of 1.

Publication using NBP1-77375	Applications	Species
Spurlock CF 3rd, Tossberg JT, Olsen NJ, Aune TM Cutting Edge: Chronic NF-kappaB Activation in CD4+ T Cells in Rheumatoid Arthritis Is Genetically Determined by HLA Risk Alleles. J Immunol 2015-08-01 [PMID: 26091715] (FLOW)	FLOW

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	Flow	Human	06/30/2014	View Summary Application Flow Cytometry Sample Tested Human PBMC Species Human

Array NBP1-77375

• Apc1 Antibodies
• Apc1 Proteins