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APC Antibody

Images

 
Immunohistochemistry-Paraffin: APC Antibody [NBP1-84994] - Staining of human skin shows strong cytoplasmic positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: APC Antibody [NBP1-84994] - Staining of human cerebral cortex shows strong positivity in neuropil.
Immunohistochemistry-Paraffin: APC Antibody [NBP1-84994] - Staining of human skeletal muscle shows low positivity in myocytes as expected.
Immunohistochemistry-Paraffin: APC Antibody [NBP1-84994] - Staining of human small intestine shows moderate to strong membranous and cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

APC Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: DNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
APC
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
APC Protein (NBP1-84994PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (87%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for APC Antibody

  • adenomatosis polyposis coli tumor suppressor
  • adenomatosis polyposis coli
  • adenomatous polyposis coli protein
  • adenomatous polyposis coli
  • APC
  • BTPS2
  • Deleted in polyposis 2.5
  • DP2
  • DP2.5DP2
  • DP3
  • FPC
  • GS
  • Min
  • Protein APC

Background

Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling (1). APC regulates

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol APC