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alpha-Fetoprotein/AFP Antibody (189508) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, KO
Clone
189508
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488
Datasheet
Reviews & Publications
Protocols & FAQs
Support & Research

alpha-Fetoprotein/AFP Antibody (189508) [DyLight 488] Summary

Immunogen
Human umbilical cord serum-derived alpha -Fetoprotein/AFP
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
AFP
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for alpha-Fetoprotein/AFP Antibody (189508) [DyLight 488]

  • AFP
  • Alpha-1-fetoprotein
  • alpha-fetoglobulin
  • alpha-Fetoprotein
  • DSCAM2
  • FETA
  • HP
  • HPAFP

Background

Alpha 1 Fetoprotein encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AFP