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ALK-7/Activin Receptor Type 1C Antibody (810506) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
810506
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

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ALK-7/Activin Receptor Type 1C Antibody (810506) [DyLight 488] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human ALK‑7
Leu26-Glu113
Accession # Q8NER5
Specificity
Detects human ALK‑7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant rat ALK-7 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ACVR1C
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ALK-7/Activin Receptor Type 1C Antibody (810506) [DyLight 488]

  • activin A receptor, type IC
  • Activin receptor type IC
  • activin receptor type-1C
  • Activin receptor-like kinase 7
  • Activin RIC
  • ACTR-IC
  • ACVR1C
  • ACVRLK7
  • ALK7
  • ALK-7
  • ALK7ALK-7
  • EC 2.7.11
  • EC 2.7.11.30

Background

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type Ireceptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interactdirectly with DNA or in complex with other transcription factors (Bondestam et al., 2001 (PubMed 12063393)).(suppliedby OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ACVR1C