Alix Antibody

Alix encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 10 of 10.

Publications using NBP1-90201	Applications	Species
Blommer J, Pitcher T, Mustapic M et al. Extracellular vesicle biomarkers for cognitive impairment in Parkinson's disease Brain : a journal of neurology 2022-07-14 [PMID: 35833836]
Busch DJ, Zhang y, Kumar A et al. Identification of RNA content of CHO-derived extracellular vesicles from a production process Journal of biotechnology 2022-03-12 [PMID: 35292346] (WB)	WB
Aiello A, Giannessi F, Percario ZA et al. HIV-1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line Viruses 2021-12-31 [PMID: 35062278] (WB, Human)	WB	Human
Yao PJ, Eren E, Goetzl EJ, Kapogiannis D Mitochondrial Electron Transport Chain Protein Abnormalities Detected in Plasma Extracellular Vesicles in Alzheimer's Disease Biomedicines 2021-10-31 [PMID: 34829816] (WB, Human)	WB	Human
Carlomagno C, Giannasi C, Niada S et al. Raman Fingerprint of Extracellular Vesicles and Conditioned Media for the Reproducibility Assessment of Cell-Free Therapeutics Frontiers in Bioengineering and Biotechnology 2021-04-13 [PMID: 33928071] (WB, Human)	WB	Human
Millan C, Prause L, Vallmajo-Martin Q et al. Extracellular Vesicles from 3D Engineered Microtissues Harbor Disease-Related Cargo Absent in EVs from 2D Cultures Advanced healthcare materials 2021-04-22 [PMID: 33890421]
Morris C, Durand S, Jalinot P Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Oncotarget 2021-03-30 [PMID: 33868586] (WB, Human)	WB	Human
Mansur RB, Delgado-Peraza F, Subramaniapillai M et al. Exploring brain insulin resistance in adults with bipolar depression using extracellular vesicles of neuronal origin Journal of psychiatric research 2020-12-04 [PMID: 33316649] (WB, Human)	WB	Human
Nogueras-Ortiz, C J, Mahairaki, V Et al. Astrocyte- and Neuron-Derived Extracellular Vesicles from Alzheimer's Disease Patients Effect Complement-Mediated Neurotoxicity. Cells 2020-07-04 [PMID: 32635578] (WB, Human)	WB	Human
Beckwith KS, Beckwith MS, Ullmann S et al. Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection Nat Commun 2020-05-10 [PMID: 32385301]

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	WB	Rat	01/17/2018	View Summary Application Western Blot Sample Tested Rat astrocytes Species Rat Lot A114984

Array NBP1-90201

• Alix Antibodies
• Alix Lysate
• Alix Proteins