Immunohistochemistry-Paraffin: AE Binding Protein 1/ACLP Antibody (1D2) [H00000165-M01] - Analysis of monoclonal antibody to AEBP1 on formalin-fixed paraffin-embedded human adrenal gland. Antibody concentration 3 ug/ml.
ELISA: AE Binding Protein 1/ACLP Antibody (1D2) [H00000165-M01] - Detection limit for recombinant GST tagged AEBP1 is approximately 0.3ng/ml as a capture antibody.
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
AEBP1 (NP_001120, 912 a.a. ~ 1013 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPSRPMTP
Specificity
AEBP1 - AE binding protein 1
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
AEBP1
Purity
IgG purified
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Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA. Use in Immunohistochemistry reported in scientific literature (PMID: 30097586).
Publications
Read Publications using H00000165-M01 in the following applications:
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for AE Binding Protein 1/ACLP Antibody (1D2)
ACLP
ACLPadipocyte enhancer binding protein 1
AE binding protein 1
AE-binding protein 1adipocyte enhancer-binding protein 1
AEBP1
Aortic carboxypeptidase-like protein
FLJ33612
Background
The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. Adipocyte-enhancer binding protein 1 may play a role in differentiated vascular smooth muscle cells.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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