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Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

Images

 
Immunohistochemistry-Paraffin: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody [NBP1-33096] - Cal27 xenograft. Activin A Receptor type I antibody dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH ...read more
Immunohistochemistry-Paraffin: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody [NBP1-33096] - Mouse prostate. Activin A Receptor type I antibody dilution: 1:500. Scale bar = M um.Antigen Retrieval: Trilogy™ ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, RM, XpSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Activin RIA/ALK-2/Activin Receptor Type 1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Activin RIA/ALK-2/Activin Receptor Type 1. The exact sequence is proprietary.
Localization
Membrane
Predicted Species
Rat (99%), Xenopus (93%), Rhesus Macaque (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ACVR1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 3
using
NBP1-33096 in the following applications:

Reactivity Notes

Xenopus laevis (93%). Canine reactivity reported by customer review.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

  • activin A receptor, type I
  • Activin RIA
  • ActivinRIA
  • ACTRI
  • ACVR1
  • ACVR1A
  • ACVRLK2
  • ALK2
  • ALK-2
  • FOP
  • SKR1
  • TSRI

Background

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP1-33096) (0)

There are no publications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP1-33096).
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Review for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP1-33096) (1) 31

Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Canine.

Reviews using NBP1-33096:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Canine
(1)
All Species
Images Ratings Applications Species Date Details
  3
reviewed by:
Faye Doherty
IHC-P Canine 06/24/2019
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedTMA tested for IHC staining
SpeciesCanine
Lot40073

Product General Protocols

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FAQs for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP1-33096) (0)

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Secondary Antibodies

 

Isotype Controls

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Recent Reviews

3
5
0
4
0
3
1
2
0
1
0

Faye Doherty
06/24/2019
Application: IHC-P
Species: Canine

Bioinformatics

Gene Symbol ACVR1