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Activin B/Inhibin beta B Antibody

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Western Blot: Activin B/Inhibin beta B Antibody [NBP2-16966] - Whole cell extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with Inhibin beta B antibody [C3], C-term diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
Western Blot: Activin B/Inhibin beta B Antibody [NBP2-16966] - Whole cell extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with Inhibin beta B antibody [C3], C-term diluted at 1:500. The ...read more
Immunohistochemistry-Frozen: Activin B/Inhibin beta B Antibody [NBP2-16966] - Analysis of zebrafish eye frozen section with at a 1:750 dilution.
Immunohistochemistry-Paraffin: Activin B/Inhibin beta B Antibody [NBP2-16966] - Human normal kidney. Inhibin beta B antibody [C3], C-term diluted at 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) ...read more

Product Details

Summary
Reactivity Hu, Mu, Ze, Rt, Po, Bv, ChSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Activin B/Inhibin beta B Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Activin B/Inhibin beta B. The exact sequence is proprietary.
Predicted Species
Rat (100%), Porcine (100%), Bovine (100%), Chicken (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
INHBB
Purity
Antigen Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Frozen Assay dependent
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris-Glycine (pH7), 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for Activin B/Inhibin beta B Antibody

  • activin AB beta polypeptide
  • Activin Beta B
  • Activin beta-B chain
  • INHBB
  • inhibin beta B chain
  • Inhibin Beta B
  • Inhibin Subunit Beta B
  • inhibin, beta B (activin AB beta polypeptide)
  • inhibin, beta B
  • Inhibin, beta-2

Background

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Bioinformatics

Gene Symbol INHBB
Uniprot