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FSHR Antibody (6E8.2F5) - BSA Free

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Western Blot: FSH R Antibody (6E8.2F5) [NBP2-36489] - WB analysis of (A) 15kDa partial recombinant Human FSHR protein and (B) lysate of HepG2 cells using FSH R antibody (clone 6E8.2F5) at 3ug/ml concentration.
Immunohistochemistry-Paraffin: FSH R Antibody (6E8.2F5) [NBP2-36489] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human rectal adenocarcinoma using FSH R antibody (clone 6E8.2F5) at 5 ug/ml ...read more
Immunohistochemistry-Paraffin: FSH R Antibody (6E8.2F5) [NBP2-36489] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human kidney using FSH R antibody (clone 6E8.2F5) at 5 ug/ml concentration.
Immunohistochemistry-Paraffin: FSH R Antibody (6E8.2F5) [NBP2-36489] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human placenta using FSH R antibody (clone 6E8.2F5) at 5 ug/ml concentration.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Eq, Fe, Gt, SyHa, Gp, Pm, Rb, ShSpecies Glossary
Applications WB, IHC
Clone
6E8.2F5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

FSHR Antibody (6E8.2F5) - BSA Free Summary

Immunogen
A synthetic peptide made to the human FSH R protein sequence (between residues 1-200). [Swiss-Prot P23945]
Localization
Cell membrane, Cytoplasm
Predicted Species
Mouse (91%), Rat (91%), Porcine (91%), Bovine (91%), Guinea Pig (92%), Rabbit (91%), Feline (90%), Canine (91%), Goat (91%), Sheep (91%), Golden Syrian Hamster (91%), Primate (96%), Equine (93%). Backed by our 100% Guarantee.
Clonality
Monoclonal
Host
Mouse
Gene
FSHR
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 2-5 ug/ml
  • Immunohistochemistry-Paraffin 2-5 ug/ml
  • Western Blot 2-3 ug/ml
Application Notes
The canonical isoform of FSHR is 78.3 kDa, however, it undergoes processing via glycosylation and the glycosylated protein runs at higher than predicted molecular weight. Under non-reducing conditions, FSHR may form dimers via disulfide bond formation.
Publications
Read Publications using
NBP2-36489 in the following applications:

Reactivity Notes

Immunogen's sequence similarity with other species: Chicken and Duck (70%), Xenopus (71%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for FSHR Antibody (6E8.2F5) - BSA Free

  • follicle stimulating hormone receptor
  • follicle-stimulating hormone receptor
  • Follitropin receptor
  • FSH R
  • FSH receptor
  • FSHR
  • FSH-R
  • LGR1
  • LGR1FSHRO
  • MGC141667
  • MGC141668
  • ODG1

Background

Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common alpha subunit and a homologous but distinct beta subunit. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, follicle-stimulating hormone receptor (FSHR), the beta subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, post-translational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-36489
Species: Hu, Mu, Rt, Po, Bv, Ca, Eq, Fe, Gt, SyHa, Gp, Pm, Rb, Sh
Applications: WB, IHC

Publications for FSHR Antibody (NBP2-36489)(8)

We have publications tested in 2 confirmed species: Human, Rat.

We have publications tested in 2 applications: IF/IHC, IHC-P.


Filter By Application
IF/IHC
(1)
IHC-P
(1)
All Applications
Filter By Species
Human
(1)
Rat
(1)
All Species
Showing Publications 1 - 8 of 8.
Publications using NBP2-36489 Applications Species
Park, SR;Kook, MG;Kim, SR;Lee, CM;Lee, JW;Park, JK;Park, CH;Oh, BC;Jung, Y;Hong, IS; Development of a novel testis-on-a-chip that demonstrates reciprocal crosstalk between Sertoli and Leydig cells in testicular tissue Experimental & molecular medicine 2024-07-01 [PMID: 38945952]
Yuan L, Hang W, Bi Y et al. G-CSF-mobilized Peripheral Blood Mononuclear Cells Combined with Platelet-rich Plasma Restored the Ovarian Function of aged rats via angiogenesis and glycolysis modulation Research Square 2022-01-20 [PMID: 37209460] (IF/IHC, Rat) IF/IHC Rat
Rossella Cannarella, Francesca Mancuso, Iva Arato, Cinzia Lilli, Catia Bellucci, Marco Gargaro, Roberto Curto, Maria C. Aglietti, Sandro La Vignera, Rosita A. Condorelli, Giovani Luca, Aldo E. Calogero Sperm-carried IGF2 downregulated the expression of mitogens produced by Sertoli cells: A paracrine mechanism for regulating spermatogenesis? Frontiers in Endocrinology 2022-11-29 [PMID: 36523595]
Basolo A, Poma AM, Macerola E et al. AUTOPSY STUDY OF TESTICLES IN COVID-19: UPREGULATION OF IMMUNE-RELATED GENES AND DOWNREGULATION OF TESTIS-SPECIFIC GENES The Journal of clinical endocrinology and metabolism 2022-10-19 [PMID: 36260523]
Lu X, Ding F, Chen Y, Ke S et Al. Deficiency of C1QL1 Reduced Murine Ovarian Follicle Reserve Through Intraovarian and Endocrine Control Endocrinology 2022-05-13 [PMID: 35560215]
Ghosh A, Roychowdhury T, Nandi R Et al. Inhibitory role of a smart nano-trifattyglyceride of Moringa oleifera root in epithelial ovarian cancer, through attenuation of FSHR - c-Myc axis J Tradit Complement Med 2021-11-12 [PMID: 34765512]

Details:
Citation using the HRP version of this antibody.
Panza S, Giordano F, De Rose D et al. FSH-R Human Early Male Genital Tract, Testicular Tumors and Sperm: Its Involvement in Testicular Disorders Life (Basel, Switzerland) 2020-12-09 [PMID: 33317204] (IHC-P, Human) IHC-P Human
Park SR, Kim SR, Lee JW et al. Development of a novel dual reproductive organ on a chip: recapitulating bidirectional endocrine crosstalk between the uterine endometrium and the ovary Biofabrication 2020-09-30 [PMID: 32998123]

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Product General Protocols

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Video Protocols

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Bioinformatics

Gene Symbol FSHR
Entrez
Uniprot