5-HT6 Antibody (2157A) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

5-HT6 is a seven transmembrane G-protein coupled 1 receptor for serotonin, with 93% homology between human and rat, and with highest expression in neurons of the striatum, cortex and hippocampus. Expression in cultured primary astrocytes from rats and glia has also been demonstrated for most brain regions. Expression in lymph node, spleen and testis has also been observed. High affinity for psychotropic drugs including tricyclic antidepressants and antipsychotics and high expression in the limbic regions suggest a role for 5-HT6 in emotional behaviors and mental illness. Lower expression of 5-HT6 in cortical layers I-V have been observe in Alzheimer's Disease brains.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array MAB9496

• 5-HT6 Antibodies
• 5-HT6 Lysate
• 5-HT6 Protein