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IRAK4 Antibody

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Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-1527
    • Availability
      Product Discontinued

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IRAK4 Antibody Summary

Immunogen
Peptide with sequence NKPITPSTYVRC corresponding to N-Terminus according to NP_057207.2, NP_001107654.1.
Epitope
N Terminus
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
IRAK4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 3.75 ug/ml
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 1:1000
Application Notes
WB: Approx. 50 kDa band observed in lysates of A431, HeLa and NIH3T3 (calculated MW of 51.5 kDa band according to NP_057207.1).
Control
HeLa Whole Cell Lysate
IRAK4 Overexpression Lysate
Publications
Read Publication using NB100-1527.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris (pH 7.3), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IRAK4 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • interleukin-1 receptor-associated kinase 4
  • IPD1
  • IRAK4
  • IRAK-4
  • NY-REN-64
  • REN64
  • Renal carcinoma antigen NY-REN-64

Background

Interleukin-1 receptor (see IL1R; MIM 147810)-associated kinases (e.g., IRAK1; MIM 300283) are important mediators in the signal transduction of Toll-like receptor (TLR, e.g., TLR4; MIM 603030) and IL1R family members, collectively referred to as TIRs. IRAK4 functions in this signal transduction pathway.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IRAK4 Antibody (NB100-1527)(1)


Reviews for IRAK4 Antibody (NB100-1527) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for IRAK4 Antibody (NB100-1527) (0)

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Control Lysate(s)

HeLa Whole Cell Lysate
IRAK4 Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

Additional IRAK4 Products

Research Areas for IRAK4 Antibody (NB100-1527)

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Blogs on IRAK4.

Check out the latest blog posts on IRAK4.
IRAK4: The "master IRAK" critical for initiating immune responses
IRAK4, also known as Interleukin-1 receptor-associated kinase 4, is a serine/threonine-protein kinase that plays a critical role in initiating innate and adaptive immune responses against foreign pathogens. It activates NF-kappaB in both Toll-like rec...  Read full blog post.
Read our latest blog and use the new citation tool on bio-techne.com

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Bioinformatics

Gene Symbol IRAK4
Entrez
Uniprot