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XPE/DDB2 Antibody (C.15200222)

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Western Blot: XPE/DDB2 Antibody (C.15200222) [NBP2-62792] - Whole cell extracts from human HeLa cells were analyzed using the antibody against DDB2 diluted 1:1,000 in PBS containing 10% milk. The position of the protein ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
C.15200222
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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XPE/DDB2 Antibody (C.15200222) Summary

Immunogen
Human DDB2 (Damage-Specific DNA Binding Protein 2)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
DDB2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000 - 1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for XPE/DDB2 Antibody (C.15200222)

  • damage-specific DNA binding protein 2 (48kD)
  • damage-specific DNA binding protein 2, 48kDa
  • Damage-specific DNA-binding protein 2
  • DDB p48 subunit
  • DDB2
  • DDBB
  • DNA damage-binding protein 2
  • FLJ34321
  • UV-damaged DNA-binding protein 2
  • UV-DDB 2
  • UV-DDB2
  • xeroderma pigmentosum group E protein
  • XP5
  • XPE/DDB2

Background

DDB2, also known as DNA damage-binding protein 2, consists of five isoforms of sizes 47.9 kDa, 26.7 kDa, 17.4 kDa, 40.7 kDa, and 26.8 kDa and is involved in repairing DNA damaged by ultraviolet light. Current research is being conducted on disorders and diseases including immunodeficiency, hepatitis, multiple sclerosis, lung cancer, ovarian cancer, skin cancer, and autosomal recessive disease. The protein has been linked to DNA repair and protein stability pathways where it interacts with CUL4A, DDB1, COPS5, ABL1, and E2F1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DDB2