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XPE/DDB2 Antibody (1F11)

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Western Blot: XPE/DDB2 Antibody (1F11) [H00001643-M01] - Detection against Immunogen (37.73 KDa) .
Western Blot: XPE/DDB2 Antibody (1F11) [H00001643-M01] - Detection against Immunogen (37.73 KDa) .

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1F11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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XPE/DDB2 Antibody (1F11) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
DDB2 (AAH00093, 1 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAPKKRPETQKTSEIVLRPRNKRSRSPLELEPEAKKLCAKGSGPSRRCDSDCLWVGLAGPQILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAP
Specificity
Reacts with damage-specific DNA binding protein 2, 48kDa.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DDB2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
This antibody is reactive against recombinant protein in WB and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for XPE/DDB2 Antibody (1F11)

  • damage-specific DNA binding protein 2 (48kD)
  • damage-specific DNA binding protein 2, 48kDa
  • Damage-specific DNA-binding protein 2
  • DDB p48 subunit
  • DDB2
  • DDBB
  • DNA damage-binding protein 2
  • FLJ34321
  • UV-damaged DNA-binding protein 2
  • UV-DDB 2
  • UV-DDB2
  • xeroderma pigmentosum group E protein
  • XP5
  • XPE/DDB2

Background

This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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H00001643-M01
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Bioinformatics

Gene Symbol DDB2
Entrez
Uniprot