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VGLUT2 Antibody (CL2952)

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Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641] - Analysis in human cerebral cortex and tonsil tissues using NBP2-46641 antibody. Corresponding VGLUT2 RNA-seq data are presented for the same tissues.
Orthogonal Strategies: Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641] - Analysis in human cerebral cortex and tonsil tissues using NBP2-46641 antibody. Corresponding VGLUT2 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641] - Staining of human kidney shows absence of immunoreactivity (negative control).
Immunohistochemistry: VGLUT2 Antibody (CL2952) [NBP2-46641] - VGLUT2 Antibody (2952) [NBP2-46641] - Staining of rat thalamus shows strong immunoreactivity in glutamatergic synapses.
Immunohistochemistry: VGLUT2 Antibody (CL2952) [NBP2-46641] - VGLUT2 Antibody (2952) [NBP2-46641] - Staining of mouse olfactory bulb shows strong immunoreactivity in glomeruli.
Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641] - Staining of human cerebellum shows strong immunoreactivity in glutamatergic synapses in the molecular and granular layers.
Immunohistochemistry: VGLUT2 Antibody (CL2952) [NBP2-46641] - VGLUT2 Antibody (2952) [NBP2-46641] - Staining of rat cerebellum shows strong immunoreactivity in glutamatergic fibers in the molecular and granular layers.
Immunohistochemistry: VGLUT2 Antibody (CL2952) [NBP2-46641] - VGLUT2 Antibody (2952) [NBP2-46641] - Staining of mouse cerebral cortex shows moderate positivity in neuropil.
Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641] - Staining of human cerebral cortex shows moderate immunoreactivity in neuropil.

Product Details

Summary
Reactivity Hu, Mu, Rt, RMSpecies Glossary
Applications IHC
Clone
CL2952
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

  

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VGLUT2 Antibody (CL2952) Summary

Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence CGFIHEDELDEETGDITQNYINYGTTKSYGATTQANGGWPSGWEKKEEFVQGEVQDSHSYKDRVDY
Epitope
NGGWPSGWEK
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SLC17A6
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Frozen Reported in scientific publication (PMID: 32337749)
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Publications
Read Publication using
NBP2-46641 in the following applications:

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions. Use in Rhesus Macaque reported in scientific publication (PMID: 32337749).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for VGLUT2 Antibody (CL2952)

  • differentiation-associated BNPI
  • differentiation-associated Na(+)-dependent inorganic phosphate cotransporter
  • differentiation-associated Na-dependent inorganic phosphate cotransporter
  • DNPI
  • solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
  • solute carrier family 17 member 6
  • vesicular glutamate transporter 2
  • VGLUT2

Background

VGLUT2 is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for VGLUT2 Antibody (NBP2-46641)(1)

We have publications tested in 1 confirmed species: Rhesus Macaque.

We have publications tested in 1 application: IHC-Fr.


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SLC17A6
Entrez
Uniprot