Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487] - Frozen human skin tissue sections were fixed with paraformaldehyde and stained. Vanilloid Receptor 1 staining is shown in red. Data courtesy of the ...read more
Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487] - Immunolocalization of VR1 in human glabrous skin.
Use in ICC/IF reported in scientific literature (PMID:33362470). WB usage was reported in scientific literature. IF: Staining of VR1 in human prostatic urethra results in fibrous staining within the epithelial cells.
transient receptor potential cation channel subfamily V member 1
transient receptor potential cation channel, subfamily V, member 1
transient receptor potential vanilloid 1a
transient receptor potential vanilloid 1b
TRPV1
Vanilloid R1
Vanilloid receptor 1
vanilloid receptor subtype 1
VanilloidR1
VR1
VR1DKFZp434K0220
Background
Vanilloid Receptor 1 (VR1), also known as capsaicin receptor, responds to both capsaicin, the pungent ingredient in hot peppers, and thermal stimuli within the noxious temperature range. This receptor is structurally related to the TRP family of ion channels and is predicted to contain 6 trans-membrane domains, a P-loop membrane domain and 3 ankyrin repeat domains. VR1 is highly permeable to divalent cations, including calcium and magnesium, as well as the monovalent cations sodium and potassium. Expression of VR1 appears to be limited to neurons within the sensory ganglia.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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