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Vanilloid R1/TRPV1 Antibody

Images

 
Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487] - Frozen human skin tissue sections were fixed with paraformaldehyde and stained. Vanilloid Receptor 1 staining is shown in red. Data courtesy of the ...read more
Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487] - Immunolocalization of VR1 in human glabrous skin.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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Vanilloid R1/TRPV1 Antibody Summary

Immunogen
Synthetic peptide corresponding to residues T(7) D L G A A A D P L Q K D T C(21) of human VR1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPV1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Frozen 1 ug/ml
  • Western Blot 1:100 - 1:2000
Application Notes
Use in ICC/IF reported in scientific literature (PMID:33362470). WB usage was reported in scientific literature. IF: Staining of VR1 in human prostatic urethra results in fibrous staining within the epithelial cells.
Control
Vanilloid R1/TRPV1 Overexpression Lysate
Publications
Read Publications using
NB120-3487 in the following applications:

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS with 1 mg/ml BSA
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Vanilloid R1/TRPV1 Antibody

  • Capsaicin Receptor
  • Osm-9-like TRP channel 1
  • OTRPC1
  • transient receptor potential cation channel subfamily V member 1
  • transient receptor potential cation channel, subfamily V, member 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • TRPV1
  • Vanilloid R1
  • Vanilloid receptor 1
  • vanilloid receptor subtype 1
  • VanilloidR1
  • VR1
  • VR1DKFZp434K0220

Background

Vanilloid Receptor 1 (VR1), also known as capsaicin receptor, responds to both capsaicin, the pungent ingredient in hot peppers, and thermal stimuli within the noxious temperature range. This receptor is structurally related to the TRP family of ion channels and is predicted to contain 6 trans-membrane domains, a P-loop membrane domain and 3 ankyrin repeat domains. VR1 is highly permeable to divalent cations, including calcium and magnesium, as well as the monovalent cations sodium and potassium. Expression of VR1 appears to be limited to neurons within the sensory ganglia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Vanilloid R1/TRPV1 Antibody (NB120-3487)(5)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Vanilloid R1/TRPV1 Antibody (NB120-3487) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TRPV1
Entrez
Uniprot