TSLP Antibody (55N1D10) - Azide and BSA Free Summary
Immunogen |
A partial recombinant TSLP protein (amino acids 27-158) was used as the immunogen for the antibody. |
Isotype |
IgG2a Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
TSLP |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin 3 - 5 ug/mL
- Western Blot 0.5 - 2 ug/mL
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
No Preservative |
Concentration |
1 mg/ml |
Purity |
Protein G purified |
Alternate Names for TSLP Antibody (55N1D10) - Azide and BSA Free
Background
TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of Tcell-attracting chemokines from monocytes, enhances the maturation of CD11c+ dendritic cells, naive CD4+, and CD8+ Tcells into proallergic effectors, and primes DCs to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory Tcells and maintenance of peripheral CD4+ Tcell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. TSLP is expressed in heart, liver and prostate.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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