Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44)) Summary
Immunogen |
HMW conjugate (FMPNLVPPKIC) |
Epitope |
F-M-P-N-L-V-P-P-K-I-C |
Localization |
Cytoplasmic |
Specificity |
NB100-66490 recognises Troponin T Type 2 (cardiac) isoform 1. In Western blotting, this reacts with reduced purified cardiac isoform, but does not react with the skeletal isoform. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
TNNT2 |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:100-1:2000
- Western Blot 1:250
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.09% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Protein G purified |
Alternate Names for Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44))
Background
Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Cardiac Troponin T Antibody (NB100-66490) (0)
Secondary Antibodies
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Isotype Controls
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