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Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44))

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Western Blot: Troponin T Type 2 (cardiac) Antibody (BGN/1288/44) [NB100-66490] - Human Heart lysate probed with MOUSE ANTI TROPONIN T CARDIAC ISOFORM 1

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
TT44 (BGN/1288/44)
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

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Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44)) Summary

Immunogen
HMW conjugate (FMPNLVPPKIC)
Epitope
F-M-P-N-L-V-P-P-K-I-C
Localization
Cytoplasmic
Specificity
NB100-66490 recognises Troponin T Type 2 (cardiac) isoform 1. In Western blotting, this reacts with reduced purified cardiac isoform, but does not react with the skeletal isoform.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNNT2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Western Blot 1:250

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44))

  • cardiac
  • CMD1D
  • CMPD2
  • dilated 1D (autosomal dominant)
  • hypertrophic 2
  • MGC3889
  • RCM3
  • TnTc
  • troponin T type 2 (cardiac)
  • troponin T, cardiac muscle

Background

Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TNNT2
Entrez
Uniprot