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TREX1 Antibody (41M5F2) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC
Clone
41M5F2
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-22394AF350
Alexa Fluor 405
NBP2-22394AF405
Alexa Fluor 488
NBP2-22394AF488
Alexa Fluor 532
NBP2-22394AF532
Alexa Fluor 594
NBP2-22394AF594
Alexa Fluor 647
NBP2-22394AF647
Alexa Fluor 700
NBP2-22394AF700
Alexa Fluor 750
NBP2-22394AF750
CoraFluor 1
NBP2-22394CL1
DyLight 350
NBP2-22394UV
DyLight 405
NBP2-22394V
DyLight 488
NBP2-22394G
DyLight 550
NBP2-22394R
DyLight 594
NBP2-22394DL594
DyLight 650
NBP2-22394C
DyLight 680
NBP2-22394FR
DyLight 755
NBP2-22394IR
FITC
NBP2-22394F
HRP
NBP2-22394H
Janelia Fluor 525
NBP2-22394JF525
Janelia Fluor 585
NBP2-22394JF585
Janelia Fluor 635
NBP2-22394JF635
Janelia Fluor 669
NBP2-22394JF669
Unconjugated
NBP2-22394
mFluor Violet 450 SE
NBP2-22394MFV450
mFluor Violet 500 SE
NBP2-22394MFV500
mFluor Violet 610 SE
NBP2-22394MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-22394
Azide and BSA Free
NBP2-80992
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TREX1 Antibody (41M5F2) [Biotin] Summary

Immunogen
Within the range of amino acids 211-350 of human TREX1 were used as immunogen for the antibody.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TREX1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TREX1 Antibody (41M5F2) [Biotin]

  • 3'-5' exonuclease TREX1
  • AGS1
  • Aicardi-Goutieres syndrome 1
  • CRV
  • DKFZp434J0310
  • DNase III
  • DRN3
  • EC 3.1.11.2
  • HERNS
  • three prime repair exonuclease 1,3' repair exonuclease 1

Background

TREX1 encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Blogs on TREX1.

Check out the latest blog posts on TREX1.
Dinosaur Protein Names: Infographic
Trex1 the protein is involved in DNA damage response. Tyrannosaurus rex (T. rex) the dinosaur lived during the Cretaceous Period. Raptor the protein is a regulator of mTOR activity. Velociraptors the dinosaurs lived during the Cretaceous Period. Learn...  Read full blog post.
Trex1 (3'-5' exonuclease TREX1, DNase III)
This gene encodes the major 3' to 5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that appears to provide proofreading for checkpoint signaling after DNA damage in response to oxidative stress and apoptosis. It is ubiqui...  Read full blog post.
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Bioinformatics

Gene Symbol TREX1