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Transglutaminase 7/TGM7 Antibody [Unconjugated]

Name: Transglutaminase 7/TGM7 Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF5426
Price: 449 USD

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Western blot shows lysates of human thyroid tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Transglutaminase 7/TGM7 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5426) followed by ...read more

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	WB
Clonality	Polyclonal
Host	Sheep
Conjugate	Unconjugated
Concentration	LYOPH

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Biotin BAF5426

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Carrier Free AF5426-SP

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Conjugate	Catalog #	Availability	Size	Price
Biotin	BAF5426

Transglutaminase 7/TGM7 Antibody [Unconjugated] Summary

Immunogen	S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Transglutaminase 7/TGM7
Specificity	Detects human Transglutaminase 7/TGM7 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross‑reactivity with recombinant human (rh) Transglutaminase 3 is observed, and less than 2% cross-reactivity with rhTransglutaminase 2, rhTransglutaminase 4, and recombinant mouse Transglutaminase 2 is observed.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Sheep
Gene	TGM7
Purity Statement	Antigen Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions

Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Transglutaminase 7/TGM7 Antibody [Unconjugated]

protein-glutamine gamma-glutamyltransferase Z
TG(Z)
TGase Z
TGase-7
TGM7
TGMZ
TGMZEC 2.3.2.13
TGZ
Transglutaminase 7
Transglutaminase Z
transglutaminase-7

Background

Transglutaminase 7 (TG7), encoded by the TGM7 gene, is also known as protein-glutamine-g-glutamyltransferase Z (Tgase Z) (1). It belongs to the family of Transglutaminases that catalyze the posttranslational modification of proteins via calcium dependent cross-linking reactions (2‑4). TG7 is ubiquitously expressed in humans (1). Members of the TGM family have been implicated in a variety of human diseases including neurodegenerative diseases, celiac disease, lamellar ichthyosis, bleeding disorders, cataract formation, atherosclerosis, and others (5).

Grenard, P. et al. (2001) J. Biol. Chem. 276:33066.
Gentile, V. et al. (1991) J. Biol. Chem. 266:478.
Chen, J.S.K. and Mehta K. (1999) Internat. J. Biochem. Cell Biol. 31:817.
Griffin, M. et al. (2002) Biochem. J. 368:377.
Kim, S-Y. et al. (2002) Neurochem. Int. 40:85.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Sheep IgG Isotype Control [Unconjugated]
5-001-A

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Bioinformatics

Gene Symbol

TGM7

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Transglutaminase 7/TGM7 Antibody [Unconjugated]

Species Glossary

Images

Product Details

Order Details

Transglutaminase 7/TGM7 Antibody [Unconjugated] Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for Transglutaminase 7/TGM7 Antibody [Unconjugated]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for Transglutaminase 7/TGM7 Antibody (AF5426) (0)

Reviews for Transglutaminase 7/TGM7 Antibody (AF5426) (0)

Product General Protocols

Video Protocols

FAQs for Transglutaminase 7/TGM7 Antibody (AF5426) (0)

Secondary Antibodies

Isotype Controls

Additional Transglutaminase 7/TGM7 Products

Blogs on Transglutaminase 7/TGM7

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Bioinformatics