TIMP-3 Antibody

TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP's inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Shinford Sun	WB	Human	08/11/2023	View Summary Application Western Blot Sample Tested fibroblast cells,fibroblasts,human lung cancer cell line,Human lung cancer tissue samples,human lung cancer Species Human Lot 7078-1P220908 Comments Comments ***Novus Innovators Program - new species or application used on a primary antibody.***
Enlarge	4 reviewed by: Ruhul Choudhury	IHC-P	Human	01/18/2017	View Summary Application Immunohistochemistry-Paraffin Sample Tested First trimester human decidua Species Human Lot 7078-1P 160127 Comments Comments Sodium Citrate antigen retrieval
Enlarge	3 reviewed by: Bryan Tinsley	IHC-P	Other	09/09/2014	View Summary Application Immunohistochemistry-Paraffin Sample Tested Sheep lymph node Species Other

Array NBP2-29478

• TIMP-3 Antibodies
• TIMP-3 ELISA Kit
• TIMP-3 Lysate
• TIMP-3 Proteins and Enzyme
• TIMP-3 ELISA