Reactivity | RtSpecies Glossary |
Applications | ELISA(Cap) |
Clone | 145701 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Immunogen | Mouse myeloma cell line NS0-derived recombinant rat TIMP-1 Cys24-Ala217 Accession # P30120 |
Specificity | Detects recombinant rat TIMP-1 in direct ELISAs. |
Source | N/A |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | TIMP1 |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | ELISA Detection: Rat TIMP-1 Biotinylated Antibody (Catalog number BAF580) Standard: Recombinant Rat TIMP-1 (Catalog number 580-RT) |
Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
Tissue Inhibitor of Metalloproteinases-1, (TIMP-1) belongs to a family of proteins that regulate the activation and proteolytic activity of the matrix metalloproteinases (MMPs). TIMP-1 is a glycoprotein produced by a wide range of cell types. It inhibits active MMP-mediated proteolysis by forming an N-terminal, non-covalent binary complex with the MMP active site. TIMP-1 also associates C-terminally with Pro-MMP-9 in a complex that may play a role in regulating activation. Independent of MMPs, TIMP-1 has been shown to play a role in tissue homeostasis.
Secondary Antibodies |
Isotype Controls |
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