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TIGAR/C12orf5 Antibody

Images

 
Immunohistochemistry-Paraffin: TIGAR/C12orf5 Antibody [NBP2-38522] - Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: TIGAR/C12orf5 Antibody [NBP2-38522] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: TIGAR/C12orf5 Antibody [NBP2-38522] - Staining of human prostate shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: TIGAR/C12orf5 Antibody [NBP2-38522] - Staining of human tonsil shows weak to moderate cytoplasmic positivity in germinal center cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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TIGAR/C12orf5 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TIGAR
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
TIGAR/C12orf5 Protein (NBP2-38522PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TIGAR/C12orf5 Antibody

  • C12orf5
  • chromosome 12 open reading frame 5
  • EC 3.1.3.46
  • probable fructose-2,6-bisphosphatase TIGAR
  • TIGAR
  • TIGARTP53-induced glycolysis and apoptosis regulator
  • transactivated by NS3TP2 protein

Background

The TIGAR gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity tothe bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions byblocking glycolysis and d

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TIGAR
Uniprot