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Recombinant Human TDP1 His Protein

Name: Recombinant Human TDP1 His Protein
Brand: Novus Biologicals
SKU: NBP2-22912
Price: 329 USD

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SDS-Page: Recombinant Human TDP1 Protein [NBP2-22912]

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	PAGE
Concentration	1 mg/ml

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Recombinant Human TDP1 His Protein Summary

Description	A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-298 of Human TDP1 Source: E.coli Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE AQKAAHKRKI SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM PQKQAEKVVI KKEKDISAPN DGTAQRTENH GAPACHRLKE EEDEYETSGE GQDIWDMLDK GNPFQFYLTR VSGVKPKYNS GALHIKDILS PLFGTLVSSA QFNYCFDVDW LVKQYPPEFR KKPILLVHGD KREAKAHLHA QAKPYENISL CQAKLDIAFG THHTKMMLLL YEEGLRVVIH TSNLIHADWH QKTQGTHL
Source	E. coli
Protein/Peptide Type	Recombinant Protein
Gene	TDP1
Purity	>90%, by SDS-PAGE

Applications/Dilutions

Dilutions	SDS-Page
Application Notes	Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
Theoretical MW	35.8 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer	20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Purity	>90%, by SDS-PAGE

Alternate Names for Recombinant Human TDP1 His Protein

EC 3.1.4
EC 3.1.4.-
FLJ11090
MGC104252
SCAN1
Tyr-DNA phosphodiesterase 1
tyrosyl-DNA phosphodiesterase 1

Background

Tyrosyl-DNA phosphodiesterase 1, also known as TDP1, is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at N-terminus, was expressed in E.coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Recombinant Human
TDP1 His Protein

NBP2-22912

Species: Hu

Applications: PAGE

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Bioinformatics

Gene Symbol

TDP1

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Recombinant Human TDP1 His Protein

Species Glossary

Images

Product Details

Order Details

Recombinant Human TDP1 His Protein Summary

Applications/Dilutions

Packaging, Storage & Formulations

Alternate Names for Recombinant Human TDP1 His Protein

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for TDP1 Recombinant Protein (NBP2-22912) (0)

Reviews for TDP1 Recombinant Protein (NBP2-22912) (0)

FAQs for TDP1 Recombinant Protein (NBP2-22912) (0)

Additional TDP1 Products

Research Areas for TDP1 Recombinant Protein (NBP2-22912)

Blogs on TDP1

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Contact Information

Product PDFs

Calculators

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Bioinformatics