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Tankyrase 1 Antibody

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Immunocytochemistry/ Immunofluorescence: Tankyrase 1 Antibody [NBP1-80947] - Staining of human cell line A-431 shows localization to nucleoplasm & nuclear membrane. Antibody staining is shown in green.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

  • Size / Catalog#QtyPrice
    NBP1-80947-25ul
    25ul
    $329.00
    4-6 Business Days
    NBP1-80947
    0.1 ml
    $499.00
    4-6 Business Days
Shipping $45.00 per order
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Support & Research

Tankyrase 1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SPDPVDGTSCCSTTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNKS
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Tankyrase 1 Recombinant Protein Antigen (NBP1-80947PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Tankyrase 1 Antibody

  • EC 2.4.2.30
  • PARP5A
  • PARP-5a
  • PARP5APARPL
  • PARPL
  • pART5
  • Poly [ADP-ribose] polymerase 5A
  • TANK1
  • Tankyrase 1
  • Tankyrase I
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
  • tankyrase-1
  • TIN1TANK1
  • TINF1
  • TINF1TNKS-1
  • TNKS
  • TNKS1TRF1-interacting ankyrin-related ADP-ribose polymerase

Background

The ~142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNKS
Entrez
Uniprot