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SUG1 Antibody

Images

 
Western Blot: SUG1 Antibody [NBP1-33309] - Sample (30 ug of whole cell lysate) A: A431 B: Hep G2 10% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: SUG1 Antibody [NBP1-33309] - Paraformaldehyde-fixed A549, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: SUG1 Antibody [NBP1-33309] - Paraffin-embedded human hepatocellular carcinoma. PSMC5 antibody diluted at 1:500.
Western Blot: SUG1 Antibody [NBP1-33309] - A. 30 ug Neuro2A whole cell lysate/extract, B. 30 ug GL261 whole cell lysate/extract, C. 30 ug C8D30 whole cell lysate/extract 10% SDS-PAGE gel, antibody dilution 1:1000.
Western Blot: SUG1 Antibody [NBP1-33309] - 30 ug PC-12 whole cell lysate/extract 10% SDS-PAGE gel, antibody dilution 1:1000.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ch, Pm, RM, Xp, ZeSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

SUG1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human PSMC5. The exact sequence is proprietary.
Localization
Cytoplasm (Potential), Nucleus
Predicted Species
Porcine (100%), Bovine (100%), Zebrafish (100%), Rhesus Macaque (100%), Primate (100%), Xenopus (100%), Chicken (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PSMC5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chimpanzee (100%), Xenopus laevis (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for SUG1 Antibody

  • MSUG1 protein
  • p45
  • p45/SUG26S protease regulatory subunit 8
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5
  • proteasome 26S ATPase subunit 5
  • Proteasome 26S subunit ATPase 5
  • Proteasome subunit p45
  • S8
  • SUG-1
  • SUG126S proteasome AAA-ATPase subunit RPT6
  • Tat-binding protein homolog 10
  • TBP10
  • thyroid receptor interactor 1
  • TRIP1Thyroid hormone receptor-interacting protein 1

Background

TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol PSMC5