Species: Hu
Applications: WB, IP, ChIP, KD
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Bv, Ch, Pm, RM, Xp, Ze
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Bioinformatics
Entrez |
Mouse Human Human |
Uniprot |
Human Human Human |
Product By Gene ID |
5705 |
Alternate Names |
- MSUG1 protein
- p45
- p45/SUG26S protease regulatory subunit 8
- proteasome (prosome, macropain) 26S subunit, ATPase, 5
- proteasome 26S ATPase subunit 5
- Proteasome 26S subunit ATPase 5
- Proteasome subunit p45
- S8
- SUG-1
- SUG126S proteasome AAA-ATPase subunit RPT6
- Tat-binding protein homolog 10
- TBP10
- thyroid receptor interactor 1
- TRIP1Thyroid hormone receptor-interacting protein 1
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