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SUG1 Antibody (SR1803)

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Western Blot: SUG1 Antibody (SR1803) [NBP3-22583] - Western blot analysis using NBP3-22583 in A431 cell lysate.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP
Clone
SR1803
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

SUG1 Antibody (SR1803) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human SUG1 (Uniprot #: P62195)
Specificity
Detects endogenous levels of total SUG1
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PSMC5
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:2000
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for SUG1 Antibody (SR1803)

  • MSUG1 protein
  • p45
  • p45/SUG26S protease regulatory subunit 8
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5
  • proteasome 26S ATPase subunit 5
  • Proteasome 26S subunit ATPase 5
  • Proteasome subunit p45
  • S8
  • SUG-1
  • SUG126S proteasome AAA-ATPase subunit RPT6
  • Tat-binding protein homolog 10
  • TBP10
  • thyroid receptor interactor 1
  • TRIP1Thyroid hormone receptor-interacting protein 1

Background

TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol PSMC5