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STRA6 Antibody

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Western Blot: STRA6 Antibody [H00064220-D01P] - Analysis of STRA6 expression in mouse stomach.
Western Blot: STRA6 Antibody [H00064220-D01P] - Analysis of STRA6 expression in transfected 293T cell line by STRA6 polyclonal antibody.Lane 1: STRA6 transfected lysate(73.50 KDa).Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity Hu, Mu, YeSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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STRA6 Antibody Summary

Immunogen
STRA6 (AAH25256.1, 1 a.a. - 667 a.a.) full-length human protein. MSSQPAGNQTSPGATEDYSYGSWYIDEPQGGEELQPEGEVPSCHTSIPPGLYHACLASLSILVLLLLAMLVRRRQLWPDCVRGRPGLPSPVDFLAGDRPRAVPAAVFMVLLSSLCLLLPDEDALPFLTLASAPSQDGKTEAPRGAWKILGLFYYAALYYPLAACATAGHTAAHLLGSTLSWAHLGVQVWQRAECPQVPKIYKYYSLLASLPLLLGLGFLSLWYPVQLVRSFSRRTGAGSKGLQSSYSEEYLRNLLCRKKLGSSYHTSKHGFLSWARVCLRHCIYTPQPGFHLPLKLVLSATLTGTAIYQVALLLLVGVVPTIQKVRAGVTTDVSYLLASFGIVLSEDKQEVVELVKHHLWALEVCYISALVLSCLLTFLVLMRSLVTHRTNLRALHRGAALDLSPLHRSPHPSRQAIFCWMSFSAYQTAFICLGLLVQQIIFFLGTTALAFLVLMPVLHGRNLLLFRSLESSWPFWLTLALAVILQNMAAHWVFLETHDGHPQLTNRRVLYAATFLLFPLNVLVGAMVATWRVLLSALYNAIHLGQMDLSLLPPRAATLDPGYYTYRNFLKIEVSQSHPAMTAFCSLLLQAQSLLPRTMAAPQDSLRPGEEDEGMQLLQTKDSMAKGARPGASRGRARWGLAYTLLHNPTLQVFRKTALLGANGAQP
Specificity
Reacts with stimulated by retinoic acid gene 6 homolog (mouse).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STRA6
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:100-1:2000
Application Notes
This antibody is reactive against tissue and transfected lysate in western blot, and as a detection antibody in ELISA. Use in Immunohistochemistry-Paraffin and Immunohistochemistry reported in scientific literature (PMID:31956331).
Publications
Read Publications using
H00064220-D01P in the following applications:

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for STRA6 Antibody

  • FLJ12541
  • MCOPS9
  • stimulated by retinoic acid gene 6 homolog (mouse)
  • stimulated by retinoic acid gene 6 protein homolog
  • STRA6

Background

The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for STRA6 Antibody (H00064220-D01P)(10)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: Block/Neutralize, IF/IHC, IHC-P, WB, Western Blot.


Filter By Application
Block/Neutralize
(1)
IF/IHC
(1)
IHC-P
(2)
WB
(2)
Western Blot
(1)
All Applications
Filter By Species
Human
(2)
Mouse
(2)
All Species
Showing Publications 1 - 10 of 10.
Publications using H00064220-D01P Applications Species
He W, Sun Y, Ge J et al. STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma Frontiers in endocrinology 2023-02-10 [PMID: 36843593] (IHC-P, Human) IHC-P Human
He W, Cheng Z, Huo Z et al. STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice Endocrinology 2023-01-02 [PMID: 36592123]
Jean M, Srinivasagan R, Johannes L et al. Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A. J Lipid Res. 2022-04-19 [PMID: 35452666]
Nishimoto K, Toya Y, Davis CR et al. Dynamics of vitamin A uptake, storage, and utilization in vocal fold mucosa Mol Metab 2020-05-28 [PMID: 32473404] (WB, Human) WB Human
Wang HM, Wu C, Jiang YY et al. Retinol and vitamin A metabolites accumulate through RBP4 and STRA6 changes in a psoriasis murine model Nutr Metab (Lond) 2020-01-13 [PMID: 31956331] (IHC-P, IF/IHC, Mouse) IHC-P, IF/IHC Mouse
Szwarc MM, Hai L, Gibbons WE et al. Retinoid signaling controlled by SRC-2 in decidualization revealed by transcriptomics Reproduction 2018-10-17 [PMID: 30325183] (Western Blot, Block/Neutralize) Western Blot, Block/Neutralize
Young PA, Leonard S, Martin DS, Findlay JB. The effect of retinol binding protein on the proteome of C2C12 muscle cells. Diabetes Metab Res Rev. 2015-11-10 [PMID: 26556762]
Breen CJ, Martin DS, Ma H, McQuaid K. Production of Functional Human Vitamin A Transporter/RBP Receptor (STRA6) for Structure Determination. PLoS One. 2015-03-27 [PMID: 25816144]
Berry DC, Levi L, Noy N. Holo-retinol-binding protein and its receptor STRA6 drive oncogenic transformation. Cancer Res. 2014-09-18 [PMID: 25237067]
Muenzner M, Tuvia N, Deutschmann C et al. RBP4 and its Membrane Receptor STRA6 Control Adipogenesis by Regulating Cellular Retinoid Homeostasis and RARalpha Activity. Mol Cell Biol. 2013-08-19 [PMID: 23959802] (WB, Mouse) WB Mouse

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Bioinformatics

Gene Symbol STRA6
Entrez
Uniprot