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SPTLC1 Antibody - BSA Free

Images

 
Western Blot: SPTLC1 Antibody [NBP2-81928] - Analysis of SPTLC1 in (A) A549 and (B) HeLa cell lysate with SPTLC1 antibody at 1 ug/ml.
Immunohistochemistry: SPTLC1 Antibody - BSA Free [NBP2-81928] - Immunohistochemistry of SPTLC1 in human lung tissue with SPTLC1 antibody at 5 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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SPTLC1 Antibody - BSA Free Summary

Immunogen
SPTLC1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SPTLC1. The immunogen is located within amino acids 380 - 430 of SPTLC1. Amino Acid Squence: HLQLEESTGSREQDVRL
Specificity
At least two isoforms of SPTLC1 are known to exist; this antibody will detect only isoform a. SPTLC1 antibody is predicted to not cross-react with SPT2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SPTLC1
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin
  • Western Blot 1 ug/ml
Theoretical MW
51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse: (88%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for SPTLC1 Antibody - BSA Free

  • EC 2.3.1.50
  • hereditary sensory neuropathy, type 1
  • HSAN1
  • LBC1
  • LCB 1
  • LCB1
  • LCB1HSAN
  • Long chain base biosynthesis protein 1
  • MGC14645
  • serine C-palmitoyltransferase
  • serine palmitoyltransferase 1
  • serine palmitoyltransferase, long chain base subunit 1
  • Serine-palmitoyl-CoA transferase 1
  • SPT 1
  • SPT1
  • SPT1HSN1
  • SPTI
  • SPTLC1

Background

Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SPTLC1