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SP-B/Surfactant Protein B Antibody

Images

 
Western Blot: SP-B/Surfactant Protein B Antibody [NBP1-57977] - Lung function in newborn and adult TNC KO and WT mice during HTV ventilation. Representative results of SP-B/Surfactant Protein B and SP-C protein ...read more
Immunohistochemistry: SP-B/Surfactant Protein B Antibody [NBP1-57977] - Human Lung Tissue Observed Staining: Cytoplasm and membrane of pneumocytes Primary Antibody Concentration: 1 : 600 Secondary Antibody: Donkey ...read more
Western Blot: SP-B/Surfactant Protein B Antibody [NBP1-57977] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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SP-B/Surfactant Protein B Antibody Summary

Description
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Immunogen
Synthetic peptides corresponding to SFTPB(surfactant, pulmonary-associated protein B) The peptide sequence was selected from the middle region of SFTPB. Peptide sequence PGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAV. The peptide sequence for this immunogen was taken from within the described region.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SFTPB
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1.0 ug/ml
Publications
Read Publications using
NBP1-57977 in the following applications:

  • WB
    2 publications

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 26092997). Use in Rat reported in scientific literature (PMID:31059017).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for SP-B/Surfactant Protein B Antibody

  • 18 kDa pulmonary-surfactant protein
  • 6 kDa protein
  • PSP-B
  • pulmonary surfactant-associated protein B
  • Pulmonary surfactant-associated proteolipid SPL(Phe)
  • SFTB3
  • SFTP3
  • SFTPB
  • SMDP1
  • SP-B surfactant, pulmonary-associated protein B
  • SP-B
  • surfactant protein B

Background

SFTPB is the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins. See also SFTPA1, SFTPC, and SFTPD. The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SP-B/Surfactant Protein B Antibody (NBP1-57977)(3)

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Bioinformatics

Gene Symbol SFTPB
Uniprot