SnoN Antibody - BSA Free

TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Like Ski, SnoN functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. SnoN is located primarily in the nucleus in cancer tissues or cells, but in the cytoplasm in normal tissues or primary epithelial cells. There are at least four alternately spliced isoforms of SnoN; SnoN antibody will recognize all isoforms (SnoN, SnoN2, SnoI, and SnoA).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using NBP1-77306	Applications	Species
Song AN, Yin XJ, Gao P Et al. Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021-11-01 [PMID: 34605572]

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	IHC-P	Human	10/02/2015	View Summary Application Immunohistochemistry-Paraffin Sample Tested Hela cell line Species Human

Array NBP1-77306

• SnoN Antibodies
• SnoN Lysate
• SnoN Proteins